Words similar to pbpk

Example sentences for: pbpk

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The approach used by PKQuest is to first use the IV input data to find the PBPK parameters for ethanol, and then, using these parameters, solve for the time dependent IV input function that would produce a blood time course identical to the time course observed with the orally administered drug.
Their subject-specific PBPK explained 91% of the observed data variability and found interindividual toxicokinetic differences.
The PBPK parameters used here are identical to those used in all the other applications of PKQuest [ 5 13 14 ] . The procedures used for choosing and refining these parameters has been described in [ 5 ] . Table 1lists the organ weights (Kg) and blood flows (liters/min/Kg) for the standard 70 Kg human.
Validity of the PBPK model
It is assumed in the PBPK model that the arterial blood and alveolar gas partial pressures are equal and correspond to the experimentally measured end tidal gas partial pressure.