Words similar to pbpk

Example sentences for: pbpk

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PBPK models have usually been applied to animal data where it is possible to accurately measure and control the relevant parameters (tissue distribution, organ blood flows, etc.).
The word "prediction" (and not "description") is purposely used here because most of the parameters are based on the default, previously determined set of PBPK data and there is a minimum of adjustable parameters.
A baseline ethanol PBPK model was developed based on the careful and detailed measurements of Norberg et al.
The PBPK parameters used here are identical to those used in all the other applications of PKQuest [ 5 13 14 ] . The procedures used for choosing and refining these parameters has been described in [ 5 ] . Table 1lists the organ weights (Kg) and blood flows (liters/min/Kg) for the standard 70 Kg human.
This new PBPK has been designed to provide a rigorous mathematical treatment that takes into consideration all the different biochemical and physiological properties that a drug may have, and yet be very simple to use.