Words similar to pax
Example sentences for: pax
How can you use “pax” in a sentence? Here are some example sentences to help you improve your vocabulary:
There followed a long period of peace and prosperity known as the Pax Romana.
We also analyzed two mutant strains that have either cell-autonomous ( Hoxa3 +/- Pax1 -/-) or non-cell-autonomous ( Rag1 -/-) TEC defects, with blocks at different stages of thymocyte differentiation.
Combined with our previous data, this result suggests that the decrease in DP cell numbers seen in the Hoxa3-Pax1 compound mutants is both due to an increase in the number of pre-DP and DP cells undergoing apoptosis as well as a decrease in the number of proliferating DP.
In the Hoxa3,Pax1 compound mutants, cell-autonomous TEC defects cause a partial block at the DN-DP transition, so thymocytes do progress to DP and SP stages, albeit at reduced frequencies [ 29 ] . TEC defects are seen as early as E12.
Our results provide direct genetic evidence for these functions of TECs, by showing that these processes are defective in mutants with a primary TEC differentiation defect (the Hoxa3,Pax1 compound mutants).