Words similar to pax
Example sentences for: pax
How can you use “pax” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the Hoxa3,Pax1 compound mutants, cell-autonomous TEC defects cause a partial block at the DN-DP transition, so thymocytes do progress to DP and SP stages, albeit at reduced frequencies [ 29 ] . TEC defects are seen as early as E12.
For general anterior segment development, this is supported by the observations that genetic deficiency of transcription factors such as PAX6, PITX2, FOXC1 [ 44, 45], and LMX1B that are expressed in the periocular mesenchyme results in anterior segment dysgenesis in both humans and mice [ 46, 47, 48, 49, 50, 51, 52, 53, 54].
Both the NYT and the WP have exuberant reaction quotes from the owner of PAX TV, but the Times wins with, "If we're going into the duopoly game, we're the prettiest girl at the du-op dance."
The reduced expression of these cytokines in Hoxa3 +/- Pax1 -/-compound mutants could be an indirect effect of defective TEC differentiation, or could be direct downstream targets since both Hoxa3 and Pax1 are expressed in fetal thymus [ 54 55 ] . Comparison of the Hoxa3 +/- Pax1 -/-phenotype with those of cytokine mutants do not reveal many similarities [ 30 46 56 57 58 59 60 61 ] , probably because of the simultaneous reductions in multiple cytokines in the Hoxa3 +/- Pax1 -/-mutants.
5 in the developing thymus, well before significant thymocyte maturation takes place [ 52 53 ] . Although the number of TECs is reduced by about 2-fold in Hoxa3 +/- Pax1 -/-compound mutants, the number of thymocytes is reduced by a slightly greater amount, around 3-fold [ 29 ] . Therefore, the reductions seen in cytokine message levels in the Hoxa3 +/- Pax1 -/-compound mutants are not secondary to decreased TEC numbers.
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