Words similar to oncotic
Example sentences for: oncotic
How can you use “oncotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
The large pores activated by MTX have been referred to as cytolytic/oncotic pores, or COP, since their activation ultimately leads to the release of lactate dehydrogenase (LDH), an indication of necrotic or oncotic cell death [ 9].
Zeiosis has been associated in many cell types with apoptosis [ 22 23 24 ] . The results of the present experiments suggest that following a brief exposure to MTX, U73343 rescues cells from oncotic cell death.
It is important to note that these MTX-induced events are only observed in the presence of U73343 and occur in the absence of a measurable rise in [Ca 2+] i . To our knowledge, this is the first evidence that MTX has effects independent of a rise in [Ca 2+] i . Perhaps more importantly, the results of the present study suggest that U73343 converts MTX-induced oncosis into apoptosis and that a rise in [Ca 2+] i is necessary for oncotic cell death.
However, at ~400 sec, ethidium uptake resumed and increased to an intermediate value as was seen in Fig 3. This secondary uptake of ethidium correlated in time with a partial LDH release (Fig 4, bottom panel, red triangles ). U73343 alone had no effect on LDH release (Fig 4, bottom panel, green squares ). These results directly demonstrate that a percentage of cells within the population died by oncosis, but perhaps more importantly, that a significant number of the cells are rescued from MTX-induced oncotic cell death when U73343 is added within a short time-window after MTX.
The cuvette experiments suggest that BAECs challenged with MTX can be rescued from oncotic cell death if U73343 is added to the bath solution within a narrow time frame after the addition of MTX.
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