Words similar to oncotic
Example sentences for: oncotic
How can you use “oncotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
It is important to note that these MTX-induced events are only observed in the presence of U73343 and occur in the absence of a measurable rise in [Ca 2+] i . To our knowledge, this is the first evidence that MTX has effects independent of a rise in [Ca 2+] i . Perhaps more importantly, the results of the present study suggest that U73343 converts MTX-induced oncosis into apoptosis and that a rise in [Ca 2+] i is necessary for oncotic cell death.
First, U73122 and U73343, compounds that are commonly used to examine PLC-dependent mechanisms, potently inhibit MTX-induced change in [Ca 2+] i , vital dye uptake, and oncotic cell death in BAECs.
Initially, MTX causes a graded increase in cytosolic free Ca 2+concentration ([Ca 2+] i ). This is followed closely in time by the opening of cytolytic/oncotic pores (COP) that allow the exchange of large organic molecules of molecular weight less than ~800 Daltons across the plasma membrane.
U73343 rescues cells from MTX-induced oncotic cell death.
The large pores activated by MTX have been referred to as cytolytic/oncotic pores, or COP, since their activation ultimately leads to the release of lactate dehydrogenase (LDH), an indication of necrotic or oncotic cell death [ 9].
Loading...