Words similar to oncotic
Example sentences for: oncotic
How can you use “oncotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, at ~400 sec, ethidium uptake resumed and increased to an intermediate value as was seen in Fig 3. This secondary uptake of ethidium correlated in time with a partial LDH release (Fig 4, bottom panel, red triangles ). U73343 alone had no effect on LDH release (Fig 4, bottom panel, green squares ). These results directly demonstrate that a percentage of cells within the population died by oncosis, but perhaps more importantly, that a significant number of the cells are rescued from MTX-induced oncotic cell death when U73343 is added within a short time-window after MTX.
First, U73122 and U73343, compounds that are commonly used to examine PLC-dependent mechanisms, potently inhibit MTX-induced change in [Ca 2+] i , vital dye uptake, and oncotic cell death in BAECs.
Zeiosis has been associated in many cell types with apoptosis [ 22 23 24 ] . The results of the present experiments suggest that following a brief exposure to MTX, U73343 rescues cells from oncotic cell death.
All of the cells treated with vehicle alone (DMSO) before MTX exhibited the typical blebbing profile and nuclear staining indicative of rapid oncotic cell death.
It is important to note that these MTX-induced events are only observed in the presence of U73343 and occur in the absence of a measurable rise in [Ca 2+] i . To our knowledge, this is the first evidence that MTX has effects independent of a rise in [Ca 2+] i . Perhaps more importantly, the results of the present study suggest that U73343 converts MTX-induced oncosis into apoptosis and that a rise in [Ca 2+] i is necessary for oncotic cell death.
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