Example sentences for: oncotic

How can you use “oncotic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Initially, MTX causes a graded increase in cytosolic free Ca 2+concentration ([Ca 2+] i ). This is followed closely in time by the opening of cytolytic/oncotic pores (COP) that allow the exchange of large organic molecules of molecular weight less than ~800 Daltons across the plasma membrane.

  • All of the cells treated with vehicle alone (DMSO) before MTX exhibited the typical blebbing profile and nuclear staining indicative of rapid oncotic cell death.

  • U73343 rescues cells from MTX-induced oncotic cell death.

  • The large pores activated by MTX have been referred to as cytolytic/oncotic pores, or COP, since their activation ultimately leads to the release of lactate dehydrogenase (LDH), an indication of necrotic or oncotic cell death [ 9].

  • However, at ~400 sec, ethidium uptake resumed and increased to an intermediate value as was seen in Fig 3. This secondary uptake of ethidium correlated in time with a partial LDH release (Fig 4, bottom panel, red triangles ). U73343 alone had no effect on LDH release (Fig 4, bottom panel, green squares ). These results directly demonstrate that a percentage of cells within the population died by oncosis, but perhaps more importantly, that a significant number of the cells are rescued from MTX-induced oncotic cell death when U73343 is added within a short time-window after MTX.


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