Example sentences for: oncoprotein

How can you use “oncoprotein” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • TOP1 has been shown to interact with many proteins including components of the holo TFIIIC complex [ 1 ] , TFIID [ 2 ] , p53 [ 3 ] , SV-40 large T antigen [ 4 ] , nucleolin [ 5 ] , the RING finger protein topors [ 6 ] , the RNA splicing factors PSF/p54 nrb [ 7 ] and SF2/ASF [ 8 ] , the cell cycle regulatory protein ARF [ 9 ] , RNA pol II complex [ 10 11 ] , and HTLV type 1 tax oncoprotein [ 12 ] . TOP1 also interacts with a variety of unidentified proteins involved in its phosphorylation, ubiquitination and sumoylation [ 13 14 15 16 17 ] .

  • The splenocytes were derived from T cell receptor transgenic mice that preferentially enhanced development of CD4 +T cells recognizing a peptide within the SV40 large T oncoprotein [ 28 ] . While the transfer of naive splenocytes from the TCR transgenic mice had no effect on tumor development, sub-lethal radiation prior to lymphocyte transfer resulted in significant reduction in tumor burden in both intervention and regression trials.

  • One of these is typified by the candidate tumor suppressor protein, H-rev107, which inhibits growth of tumors induced by the oncoprotein H-Ras [ 58].

  • Cdc37 encodes a 50-kDa protein that targets intrinsically unstable oncoprotein kinases including Cdk4, Raf-1, and v-src to the molecular chaperone Hsp90, an interaction that is thought to be important for the establishment of signaling pathways.


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