Example sentences for: oncosis

How can you use “oncosis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, at ~400 sec, ethidium uptake resumed and increased to an intermediate value as was seen in Fig 3. This secondary uptake of ethidium correlated in time with a partial LDH release (Fig 4, bottom panel, red triangles ). U73343 alone had no effect on LDH release (Fig 4, bottom panel, green squares ). These results directly demonstrate that a percentage of cells within the population died by oncosis, but perhaps more importantly, that a significant number of the cells are rescued from MTX-induced oncotic cell death when U73343 is added within a short time-window after MTX.

  • It is important to note that these MTX-induced events are only observed in the presence of U73343 and occur in the absence of a measurable rise in [Ca 2+] i . To our knowledge, this is the first evidence that MTX has effects independent of a rise in [Ca 2+] i . Perhaps more importantly, the results of the present study suggest that U73343 converts MTX-induced oncosis into apoptosis and that a rise in [Ca 2+] i is necessary for oncotic cell death.

  • BAECs rescued from oncosis by U73343 die by apoptosis.

  • Zeiosis is a type of membrane blebbing associated with apoptosis [ 22 23 24 ] . Since U73343 protects cells from MTX-induced oncosis and causes zeiosis, we considered the possibility that the cells surviving the initial insult may ultimately die by apoptosis.

  • The same pattern was observed when U73343 was added 4 min after MTX, i.e., full protection from oncosis with ~40% zeiosis.


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