Example sentences for: oncogenic

How can you use “oncogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These proteins could have a potentially important role in the regulation of cell growth, as TAX1BP, CREB3 and TARBP possess anti-apoptotic, tumor suppressor and oncogenic activities [ 23, 24, 25], respectively.

  • This oncogenic mutation has been found in human basal cell carcinoma [ 3 ] and the correspondingly mutated protein is capable of ligand-independent activation of the Hh pathway in cell-culture assays [ 11 ] . A kinetic and saturation binding assay with Smo act-containing membranes showed that this mutant protein binds the Hh agonist with an affinity identical to that of Smo wt(data not shown).

  • STAT1, another signaling intermediate in the IL-6 pathway, has been observed to be activated in non-tumorigenic cells, and may function as a "check" for STAT3 phosphorylation, a possible oncogenic event [ 30 31 ] . We are investigating whether or not STAT1 is phosphorylated by JAK2 in NRP-152 cells, and whether STAT1 phosphorylation is required for the survival of NRP-152 cells.

  • This extraordinary plasticity has a price: V(D)J recombination can produce self-reactive receptors leading to autoimmune disease [ 38, 39] and may err to create oncogenic chromosomal translocations [ 40].

  • A number of studies have employed a variety of techniques to detect changes in gene expression associated with the oncogenic state and have reported selective elevation of specific RP transcripts in tumors.


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