Words similar to oncogenesis
Example sentences for: oncogenesis
How can you use “oncogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:
In an effort to develop a model for studying the effects of Pten inactivation in mammary oncogenesis, we have introduced an additional genetic alteration, an MMTV- Wnt-1 transgene, by breeding Pten heterozygotes [ 25] with MMTV- Wnt-1 transgenic (TG) mice [ 27].
Results presented here and published earlier [ 15, 16, 17, 18, 26] have clearly demonstrated the significant impact of Pten on mammary oncogenesis.
Mouse models are valuable research tools for the study of the molecular mechanisms of oncogenesis and for the testing and screening of cancer therapeutic agents targeted to specific oncogenic lesions.
It has been proposed that loss of hERα expression in breast tumors is the result of aberrant RNA processing [ 40 41 42 43 ] . These aberrantly spliced mRNAs, if translated, could lead to truncated receptors with hormone binding but not DNA binding function [ 44 ] . Further, there is evidence for the role of RNA processing in oncogenesis [ 45 46 ] . Many studies, including those on human hnRNP A2/B1 and the CD44 gene, suggest that high fidelity pre-mRNA splicing is critical to normal cellular function and may play a key role in oncogenesis and breast cancer progression [ 47 48 ] . The strong association between nmt55/p54 nrband hERα expression indicates that nmt55/p54 nrbmay be an important marker for breast cancer progression.
They used an annotation-based pathway database, which classified differentially expressed genes into three major groups: immune and inflammatory response; oncogenesis, cell proliferation, and growth; or structure and permeability.
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