Words similar to oncogenes
Example sentences for: oncogenes
How can you use “oncogenes” in a sentence? Here are some example sentences to help you improve your vocabulary:
Among 181 NNBC patients who had undergone breast-conserving therapy or modified mastectomy combined with axillary lymphadenectomy of level 1 and 2 (at least 10 lymph nodes per patient had been removed), c- myc and HER-2 / neu oncogenes were assessed prospectively using double differential PCR.
Many other associated mutation or amplification of oncogenes, tumor suppressor genes including p53, K-ras, N-ras and N-myc, etc. are frequently seen, but the roles of these gene mutations/amplifications in pathogenesis of the tumor remain largely unclear [ 4 ] ; [ 5 ] . The alveolar subtype of rhabdomyosarcoma, however, is consistently associated with two common chromosomal translocations.
Cdc37 expression may not only be required to support proliferation in cells that are developmentally programmed to proliferate, but may also be required in cells that are inappropriately induced to initiate proliferation by oncogenes.
Cytogenetic and molecular genetic analyses have identified the short arm of chromosome 5, 5p, as frequently affected by duplications and deletions in a high proportion of CCs [ 3 4 5 6 ] . These findings suggest the presence of positively regulated amplified oncogenes and negatively regulated tumor suppressor genes (TSGs) on this chromosomal arm.
Although less frequent, 1p gains are also common to many tobacco-associated malignancies [ 11 13 14 15 16 ] . Work by Racz and colleagues suggest that PAX7 and ENO1 may be candidate oncogenes in this region [ 21 ] . PAX7 is part of a family of transcription factors known to be carcinogenic.