Words similar to oncogene

Example sentences for: oncogene

How can you use “oncogene” in a sentence? Here are some example sentences to help you improve your vocabulary:

MCF-7 cells are known to have fewer than five copies of the Her2/neu gene, whereas HCC1954 cells overexpress the protein because of gene amplification [ 40 41 ] . Her2/neu protein levels were determined with a Her2/neu ELISA kit (Oncogene) in accordance with the manufacturer's instructions.
In addition to its effects on mRNA of c-myc and p53, RU486 significantly increased that of the oncogene mdm2 by approximately 20% (Fig 2B).
Instead, GSK3β may provide the link between p53 and non-DNA damage mechanisms for p53 activation, such as oncogene activation.
The protein product of the mdm2 oncogene is over-expressed in a considerable number of tumors [ 27 ] . This protein is a pivotal negative regulator of p53 [ 27 ] ; it interacts with the P53 protein masking its transcriptional domain and accelerating its proteasomal degradation [ 21 27 ] . The later process involves the deacetylation and ubiquitylation of the p53 protein by mdm2 [ 28 ] . Inactivation and/or degradation of p53 diminishes the cell ability to undergo apoptosis [ 21 ] . Conversely, p53 may influence mdm2.
A cutoff value of 2.1 AGCN for c- myc oncogene led to the best distinction between patients.