Words similar to oncogene

Example sentences for: oncogene

How can you use “oncogene” in a sentence? Here are some example sentences to help you improve your vocabulary:

In order to derive relevant information regarding the effects of oncogene amplification on the course of breast cancer disease, the accumulated values were determined after postoperative periods of 36 and 95 months.
GSK3β-dependent phosphorylation of p53 at serine 33 may be part of other p53-regulatory pathways, such as oncogene activation or apoptosis, which are not directly activated by DNA-damage.
BRCA1 ribonuclease protection probe was made using an in vitro transcription kit (Ambion, Inc, Austin, TX, USA) as previously described [ 10] and derived clones were tested for protein levels by Western blot analysis using an anti-BRCA1 (Oncogene Research, Ab-1, Cambridge, MA, USA) antibody.
The protein product of the mdm2 oncogene is over-expressed in a considerable number of tumors [ 27 ] . This protein is a pivotal negative regulator of p53 [ 27 ] ; it interacts with the P53 protein masking its transcriptional domain and accelerating its proteasomal degradation [ 21 27 ] . The later process involves the deacetylation and ubiquitylation of the p53 protein by mdm2 [ 28 ] . Inactivation and/or degradation of p53 diminishes the cell ability to undergo apoptosis [ 21 ] . Conversely, p53 may influence mdm2.
One hundred thousand cells were separated by 5% SDS-PAGE, transferred by wet-transfer to PVDF membrane, and blotted as described above using monoclonal antibody specific for the N-terminus of BRCA1 (Oncogene Boston, MA).