Words similar to nucleosome
Example sentences for: nucleosome
How can you use “nucleosome” in a sentence? Here are some example sentences to help you improve your vocabulary:
In concert with the unrelated acidic protein N1/N2, which binds histones H3 and H4, they act together and with other factors to assemble nucleosomes [ 2 3 ] . In addition to assembly, nucleoplasmin and other proteins are involved in the chromatin remodeling and nucleosome disassembly that occurs, for example, during transcription to allow the access of transcription factors to nucleosomal DNA [ 4 ] . Another major function of nucleoplasmin is the decondensation of sperm chromatin at fertilization.
Cross-validation tests of 14 different properties such as DNA bendability and nucleosome positioning (compiled in [ 46]) showed that stacking energy delivered the best classification results for both human and Drosophila sequences when combined with the sequence probabilities.
Recent experiments have suggested that transcription factors that do not physically interact may still co-activate gene expression as long as their binding sites are spaced within a nucleosome length (approximately 150 bp), due to collaborative competition of the bound transcription factors with core histones [ 8 ] .
A nucleic acid binding domain in the C-terminus of nucleophosmin is also lacking in NPM3 and nucleoplasmin, but the known functions of nucleoplasmin in nucleosome assembly and sperm decondensation suggest that this protein, and possibly NPM3, can accomplish intermolecular reactions involving nucleic acids in other ways, perhaps by associating with other proteins that have this binding activity.
Recent studies have shown that apoptosis was accentuated in kidneys of S rats during development of nephrosclerosis [ 7 ] . These studies demonstrated increased numbers of TUNEL-positive cells, increased cytoplasmic nucleosome content and caspase-3 activation in kidneys of hypertensive S rats, compared to normotensive Sprague-Dawley control rats on the same high-salt diet.
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