Words similar to nucleosomal
Example sentences for: nucleosomal
How can you use “nucleosomal” in a sentence? Here are some example sentences to help you improve your vocabulary:
In concert with the unrelated acidic protein N1/N2, which binds histones H3 and H4, they act together and with other factors to assemble nucleosomes [ 2 3 ] . In addition to assembly, nucleoplasmin and other proteins are involved in the chromatin remodeling and nucleosome disassembly that occurs, for example, during transcription to allow the access of transcription factors to nucleosomal DNA [ 4 ] . Another major function of nucleoplasmin is the decondensation of sperm chromatin at fertilization.
Other studies have demonstrated that acidic activators can relieve nucleosomal repression and that the anti-repression function may be mediated by chromatin remodeling systems [ 39].
Some of these activities include nucleic acid binding [ 11 ] , ribonuclease activity (for processing preribosomal RNA) [ 12 ] and association with maturing preribosomal ribonucleoprotein particles [ 13 14 ] . It may also be involved in the transport of ribosomal or other nucleosomal proteins across the nuclear membrane, as it is known to shuttle between the cytoplasm and nucleus and to stimulate the nuclear importation of proteins [ 15 16 ] . Nucleophosmin also appears to be intimately involved in centrosome duplication.
Previous reports indicating a lack of apoptosis in attached gels were based on analyses using an ELISA that did not allow detection of events in apoptosis which precede the formation of a nucleosomal ladder [ 50 ] . Experiments aimed at evaluating keloid fibroblasts in attached gels were confounded by the ability of these fibroblasts to contract the gels and cause partial gel relaxation with concomitant apoptosis (Figs.
Preliminary evidence suggests preferred ligands for PPAR activation are 18 C and 20 C FAs, as FAs shorter than 14 C or longer than 20 C will not fit correctly into the PPAR binding pocket and stabilize the AF-2 helix [ 17 ] . The net effect would be that PPAR co-activators are not recruited to relax nucleosomal DNA and allow transcription machinery to interact with various promoter elements.
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