Example sentences for: nucleolar

How can you use “nucleolar” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Surprisingly, cdc5-1 cells grown at 25°C could exit mitosis despite persistent nucleolar localization of Cdc14, which may have been due to release of a small fraction of Cdc14 that was nevertheless sufficient to drive exit from mitosis in these cells.

  • Although Cdc5 activity (1) is necessary to free nucleolar Cdc14 in late mitosis, (2) can elicit ectopic release of Cdc14 in pre-anaphase cells when overproduced, (3) regulates the phosphorylation state of Net1 during anaphase, and (4) can disassemble native and recombinant RENT complexes in vitro by phosphorylating Net1, a combination of in vivo and in vitro phosphosite mapping and mutagenesis experiments suggest that Cdc5 mediates exit from mitosis primarily by phosphorylating targets other than Net1.

  • The ΔN4 fusion protein shows mostly diffuse localization but nucleolar localization is still evident (Figure 4H).

  • The K695T fusion protein is not evenly distributed throughout the outer nucleolar region but shows areas of concentration and larger central holes.

  • The most parsimonious model that unifies all of these observations is as follows: Tem1 functions upstream of Cdc15, which in turn activates the Dbf2-Mob1 protein kinase complex [ 46 47 48 49 ] . Together with Cdc5, these proteins dislodge Cdc14 from nucleolar Net1.


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