Words similar to nsf
Example sentences for: nsf
How can you use “nsf” in a sentence? Here are some example sentences to help you improve your vocabulary:
Despite the general interest in investigating the function of all Arabidopsis genes by year 2010 http://www.nsf.gov/pubs/2001/nsf01162/nsf01162.html, and the knowledge on the number and classification of Arabidopsis TFs [ 3 ] , no resource is currently available to obtain all the Arabidopsis TF sequences or information on their possible binding sites.
A high-energy physicist once told me, when I asked her what she was working on, "I couldn't possibly put it into words"--yet she continues to receive NSF funding, which suggests someone understands what she is up to on her grant applications.
The initial step of the insertion can proceed in the presence of either Mg.ATP or a non-hydrolyzable ATP-analog and involves oligomerization of the BchD and BchI subunits to form an oligomeric ring of AAA protomers that resembles the ring structure of NSF and other AAA proteins [ 14 32 ] . The second step of the insertion involves an obligatory hydrolysis of ATP that is tightly coupled with the transfer of the chelated Mg 2+to the protoporphyrin ring by BchH [ 49 ] . Although the details differ from midasin, particularly with respect to the subunit composition of the AAA ring, this chelation reaction provides a structural model suggesting that the function of the midasin M-domain may be to regulate the ATPase activity of the AAA protomers in the pseudo-hexameric ring and thus couple ATP hydrolysis to the binding of a protein ligand at the MIDAS site.
However, such primordial di-protomeric AAA polypeptides would have to have been simpler than those present in NSF, ClpA and p97 and other AAA proteins of the current era, for the latter assemble into two-tiered hexameric assemblies, with the axis joining the two protomers in each polypeptide oriented perpendicular to the plane of the hexameric ring [ 14 ] . We cannot, at present, exclude an alternative model for midasin structure in which the hexameric AAA ring assembly is a dimeric two-layered structure formed by two midasin polypeptides arranged laterally with all six odd-numbered protomers in one layer and all six even-numbered protomers in the other.
This research was supported by NIH ICIDE and ABC Training grant numbers: D43 TW01142 and U19 AI45511 and NSF Grant DEB-0083602.
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