Example sentences for: nsclc

How can you use “nsclc” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Nonetheless, studies presented here provide a basis for the rational development of “second generation” kinase inhibitors for use in NSCLC.

  • Several mutations have been identified in the context of epidermal growth factor receptor (EGFR) in patients with NSCLC that are associated with clinical response to the small-molecule EGFR inhibitors gefitinib (Iressa) or erlotinib (Tarceva) [7,8,9], including in-frame deletions such as del L747–E749;A750P in exon 19, or L858R in exon 21.

  • It has also been shown that aspirin inhibited nitrosamine induced lung carcinogenesis [ 27 ] , and it reduced COX-2 enzyme levels in lung cancer cell lines [ 28 ] . Further support for a potential role of the COX-2 pathway in lung cancer development comes from several investigations that demonstrated COX-2 overexpression in human lung tumors, specifically NSCLC [ 29 30 31 32 ] and precursor lesions [ 33 ] . While COX-2 expression was generally shown to be increased in NSCLC and to a much lesser extent in SCLC, the role of COX-2 expression in latter tumor type is difficult to determine, due to the fact that the numbers of SCLC tumors examined in these studies was very small.

  • Plasma cytokines in individuals with NSCLC

  • A Basis for Resistance to Small-Molecule EGFR Inhibitors in NSCLC


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