Words similar to nrbin

Example sentences for: nrbin

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Our studies on nmt55 and those of p54 nrbhave characterized this protein as an RNA binding protein with the ability to associate with Topoisomerase I and the polypyrimidine tract-binding protein associated splicing factor (PSF) [ 16 17 18 19 20 ] . Further, we observed the association of nmt55/p54 nrbwith several splicing factors known to be essential for spliceosome formation suggesting a role for nmt55/p54 nrbin pre-mRNA splicing (unpublished results).
We further developed, nmt55/p54 nrbspecific, site-directed polyclonal antibodies to the amino terminal region and to a mid-region to assess the potential presence of multiple nmt55/p54 nrbisoforms or processed nmt55/p54 nrbin human breast tumors.
Our previous studies investigated the protein expression of nmt55/p54 nrbin human breast tumors using a monoclonal antibody with an epitope localized to the carboxyl terminal domain of this protein.
Interestingly however, polyclonal antibody NMT- 4 detected nmt55/p54 nrbin only 3 out of 5 ER+ tumors.
The inability of polyclonal antibody NMT-4 to detect nmt55/p54 nrbin some ER+ tumors may be attributed to proteolysis during nuclear extraction and analyses or biochemical modification of functionally distinct isoform.