Example sentences for: nr

How can you use “nr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • NMDA receptors containing NR2B subunits are present in the neonatal forebrain, and over the course of development, they are replaced or supplemented with NR2A-containing receptors [ 13, 20].

  • By contrast, a peptide corresponding to GRIP1 NR box 2 did compete for this interaction [ 40 41 ] . This finding suggests that agonist-bound ERβ does not recognize ID motifs, and that ERβ interactions with N-CoR more closely resemble those with GRIP1.

  • Recently, it was discovered that bile acids are the natural ligands for a nuclear receptor termed farnesoid x receptor (FXR; NR1H4) [ 10 11 12 ] . Therefore, bile acids may be important regulators of gene expression in the liver and intestines.

  • In the list of 230 genes, cerebellum-specific genes, such as Purkinje cell protein 2 (PCP-2) and N -methyl-D-aspartate (NMDA) receptor NR2C subunit, were identified as being specifically expressed in the cerebellum and not the amygdala, consistent with expectations [ 17, 18].

  • Other NR coactivators include TRAP220 [ 7 ] , which is part of a larger complex (TRAP/DRIP/SMCC/mediator) that contacts the basal transcription machinery and PGC-1 [ 8 ] , a cold inducible coactivator that binds CBP and SRC-1 and proteins involved in RNA processing [ 9 ] . NR corepressors include NR corepressor (N-CoR) and silencing mediator of retinoid and thyroid responsive transcription (SMRT) [ 4 ] . Both N-CoR and SMRT repress transcription, at least in part, by binding to histone de-acetylases (HDACs) either directly or indirectly through other corepressor complex components.


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