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Example sentences for: npm

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NPM3 cDNA.
The apparently ubiquitous expression and abundant levels of NPM3 RNA are consistent with other members of this gene family and with a proposed role as a molecular chaperone.
To enable an amino acid comparison between NPM3 with other members of the nucleophosmin/nucleoplasmin family, we searched the nonredundant GenBank database using human NPM3, Xenopus nucleoplasmin and human nucleophosmin as BLASTP queries, and 11 additional full-length proteins were retrieved (Table 2).
NPM3 has the same exon structure as the mouse ortholog and is located approximately 5.5 kb upstream of FGF8, in the same transcriptional orientation (Figure 1B).
A nucleic acid binding domain in the C-terminus of nucleophosmin is also lacking in NPM3 and nucleoplasmin, but the known functions of nucleoplasmin in nucleosome assembly and sperm decondensation suggest that this protein, and possibly NPM3, can accomplish intermolecular reactions involving nucleic acids in other ways, perhaps by associating with other proteins that have this binding activity.