Words similar to non-synonymous
Example sentences for: non-synonymous
How can you use “non-synonymous” in a sentence? Here are some example sentences to help you improve your vocabulary:
Early tools using phylogenetic and structural information have shown promise in predicting the functional consequences of a mutation [ 13 ] . These reports predict that anywhere between 20-36% of non-synonymous SNPs alter the function of a gene's protein product.
A number of cases of positive selection at the molecular level have been supported by comparison of the rates of synonymous (K s ) and non-synonymous (K a ) substitution [ 3].
For each orthologous gene set, pairwise estimates of the synonymous (K s ) and non-synonymous (K a ) substitution rates were obtained from nucleotide-coding sequence alignments using the Pamilo-Bianchi-Li method [ 34, 35] implemented in the PBLtest program (I.B.R.
From this analysis, we estimated the rates of total synonymous and non-synonymous substitutions for 200 fragments that were aligned in-frame and then analyzed with the program NAGV2 [ 26 ] using the methods of Nei and Gojobori [ 27 ] . The results of these analyses show that the average nucleotide diversity between the two species is 2.59% ± 0.06% (range 0% to 18.
Comparison of the levels of synonymous (amino-acid preserving) and non-synonymous (amino-acid altering) nucleotide mismatches, between hits containing unverifiable stop codons or frameshift mutations and the most similar registered EPK, was used to identify additional probable pseudogenes and sequencing artifacts.