Example sentences for: non-synonymous

How can you use “non-synonymous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Early tools using phylogenetic and structural information have shown promise in predicting the functional consequences of a mutation [ 13 ] . These reports predict that anywhere between 20-36% of non-synonymous SNPs alter the function of a gene's protein product.

  • For each orthologous gene set, pairwise estimates of the synonymous (K s ) and non-synonymous (K a ) substitution rates were obtained from nucleotide-coding sequence alignments using the Pamilo-Bianchi-Li method [ 34, 35] implemented in the PBLtest program (I.B.R.

  • Abcg8 . However, only one non-synonymous nucleotide change, G1754T, resulting in a conservative cysteine substitution for glycine at amino acid 583 (Gly583Cys) in sterolin-1 was identified (Fig.

  • Synonymous and non-synonymous substitution rates were calculated by the Synonymous/non-synonymous Analysis Program (SNAP) provided by Los Alamos National Laboratory http://hiv-web.lanl.gov/using the codon-based NA alignment of the high homology group.

  • Comparison of the levels of synonymous (amino-acid preserving) and non-synonymous (amino-acid altering) nucleotide mismatches, between hits containing unverifiable stop codons or frameshift mutations and the most similar registered EPK, was used to identify additional probable pseudogenes and sequencing artifacts.


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