Example sentences for: non-transgenic

How can you use “non-transgenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Transgenic p53 heterozygous mice were then crossed with non-transgenic p53 heterozygotes to produce β-catenin transgenic, p53 null mice.

  • Splenocytes from TCR or non-transgenic C3H mice were isolated.

  • In order to determine if cyclin D 1 plays a role in this hyperplasia, kidneys from three proteinuric 40-day old transgenic siblings and three non-transgenic littermates were stained by immunohistochemistry with antibody to phospho-pRb (Ser780), a site of cyclin D 1 /CDK-4/6 phosphorylation not targeted by cyclin E/CDK-2 complexes that disrupts pRb/E2F binding for G 1 → S progression [ 24 ] . Figure 1depicts the intense, heterogeneous nuclear staining of glomerular podocytes and tubular epithelium from hyperplastic nephrons in the diseased transgenics versus the absent staining of nephrons in the non-transgenics consistent with the very low mitotic index in normal kidneys of adult animals [ 26 ] . This suggests that cyclin D 1 is promoting cell-cycle progression during the proliferation of epithelium in diseased kidneys.

  • While a number of transgenic animals died in the first nine months, the percentage of animals surviving was not significantly different between the transgenic and non-transgenic groups (Table 1).

  • hCARΔcyt was not detected in non-lymphoid tissues nor on lymphocytes from non-transgenic littermate controls (data not shown).


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