Words similar to non-steroidal
Example sentences for: non-steroidal
How can you use “non-steroidal” in a sentence? Here are some example sentences to help you improve your vocabulary:
GS-E is one of a family of diacylhydrazines that have been found to act as non-steroidal ecdysone mimics that can function as gene inducers [ 16 ] .
Regular use of aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) has been consistently associated with reduced risk of colorectal cancer and adenoma [ 1 2 3 4 ] , and there is some evidence for a protective effect for other types of cancer [ 5 6 7 8 9 ] . It is widely thought that the mechanism by which these drugs affect cancer risk is through the inhibition of the cyclooxygenase (COX) enzymes: the constitutively expressed COX-1 and the induced (in most tissues) COX-2 [ 10 ] . By inhibiting these enzymes, NSAIDs can inhibit prostaglandin synthesis, enhance cellular immune response, or induce of apoptosis, all of which have been postulated to be involved in carcinogenesis [ 11 12 13 ] .
Regular use of aspirin and other non-steroidal anti-inflammatory dugs (NSAIDs) has been consistently associated with reduced risk of colorectal cancer and adenoma [ 1 2 3 4 ] , possibly due to NSAID-related inhibition of prostaglandin synthesis, enhancement of cellular immune response, or induction of apoptosis [ 5 6 7 8 ] . A number of epidemiological studies have investigated the potential protective effect of NSAIDs with respect to other cancer sites.
The gastric mucosal responses to non-steroidal anti-inflammatory drugs also involve the activation of NF-κB, generation of cytotoxic cytokines like TNFα and epithelial apoptosis [ 6 7 ] . Administration of low concentrations of nitric oxide by an ester linkage reduces this effect, suggesting that nitric oxide was offering benefit by quenching other radicals involved in cell activation.
The second set of analyses (fully adjusted) were adjusted for all covariates and potential confounders: age, sex, race, poverty to income ratio, body mass index, prevalent cardiovascular disease, prevalent diabetes, prevalent chronic inflammatory condition, current acute illness, and use of alcohol, non-steroidal anti-inflammatory medication, aspirin, and estrogen replacement.
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