Words similar to nmr
Example sentences for: nmr
How can you use “nmr” in a sentence? Here are some example sentences to help you improve your vocabulary:
Preparation for NMR
The claim that such turbidity did not affect 13C-NMR measurements [ 3 5 6 ] contrasts with evidence that even small multimers can change NMR chemical shifts [ 25 26 ] . It should be noted also that, at high concentrations of B =, extensive, reversible self-association of B =can lead to apparently stable supersaturation with no separation of an insoluble phase [ 2 ] . For example, at pH 8.5 and a UCB concentration of 20 μM (63 times S), the weight-average aggregation number of UCB has been found to be 7.17 [ 18 ] , corresponding to a molecular weight of 4,195.
The crystal structure of gp120 (1gcl) [ 13 ] was retrieved from the pdb ( http://www.rcsb.org) and the V3 loop, created by homology modeling {(based on the nmr structure of the V3 loop from 1ce4) using the SWISS-MODEL [ 24 ] automated comparative protein modeling server ( http://www.expasy.ch/SWISS-MODEL.html} was attached to the gp120 crystal structure using Quanta's protein design module.
All crystallographically characterized metallo-β-lactamases have a flexible amino acid chain that extends over the active site [ 37 42 44 45 46 47 48 49 ] . Previous NMR studies on CcrA have shown that this loop "clamps down" on substrate or inhibitor upon binding, and there is speculation that the distortion of substrate upon clamping down of the loop may drive catalysis [ 50 ] . The crystal structure of L1 showed that there is a large loop that extends over the active site, and modeling studies have predicted that two residues, Ile164 and Phe158, make significant contacts with large, hydrophobic substituents at the 2' or 6' positions on penicillins, cephalosporins, or carbapenems [ 37 ] . To test this prediction, Ile 164 and Phe158 were changed from large, hydrophobic residues to alanines to afford the I164A and F158A mutants.
UCB, unconjugated bilirubin; H 2 B, UCB diacid; B =, UCB dianion; DMSO, dimethylsulfoxide; MBR, mesobilirubin XIIIα; N = mole fraction of DMSO in DMSO-aqueous buffer systems; NMR, nuclear magnetic resonance; S, solubility of UCB or MBR at a given pH; S o , solubility of UCB diacid.
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