Words similar to nmt
Example sentences for: nmt
How can you use “nmt” in a sentence? Here are some example sentences to help you improve your vocabulary:
These results suggested the presence of nmt55/p54 nrbvariants in a subset of ER+ human breast tumors.
The observations made here further suggest the presence of nmt55/p54 nrbvariants in a subset of ER+ human breast tumors.
Our data suggests that nmt55/p54 nrbmay be critical to cell growth and function, such that, decreased nmt55/p54 nrbexpression in ER- human breast tumors or the expression of nmt55/p54 nrbvariants in ER+ tumors may indicate loss of normal growth, nmt55/p54 nrbhas been shown in several studies to bind RNA and interact with PSF and Topoisomerase I [ 14 16 17 18 19 20 39 ] . Those results along with our observations that nmt55/p54 nrbassociates with several splicing factors essential for spliceosome formation (unpublished) and relates to tumor hormonal status [ 13 ] suggest that nmt55/p54 nrbmay be involved in pre-mRNA processing.
These studies demonstrated a statistically significant association between nmt55/p54 nrbprotein expression, tumor hormonal phenotype and mean tumor size [ 13 ] . Specifically, in tumors large in size or those tumors which were determined to be ER-, the expression of nmt55/p54 nrbprotein was absent, or greatly reduced [ 13 ] . These results suggested that loss of nmt55/p54 nrbprotein expression may be related to hormone insensitivity, tumor differentiation state, unregulated tumor growth and metastases.
We have previously shown that nmt55/p54 nrbprotein was expressed in most ER+/PR+ human breast tumors but was undetectable in ER-/PR- human breast tumors [ 13 ] . Since loss of hERα expression is associated with poor prognosis and continued expression of hERα is associated with disease-free survival and correlates well with tumor differentiation state, we wanted to investigate the regulation of nmt55/p54 nrbexpression.
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