Words similar to nmt-

Example sentences for: nmt-

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The inability of polyclonal antibody NMT-4 to detect nmt55/p54 nrbin some ER+ tumors may be attributed to proteolysis during nuclear extraction and analyses or biochemical modification of functionally distinct isoform.
These results have been reproduced in the nuclear extracts of approximately forty human breast tumors suggesting that there is an alteration or modification in the amino terminal domain of nmt55/p54 nrbthat prevents polyclonal antibody NMT-4 from binding to nmt55/p54 nrbprotein.
A plausible explanation for the lack of nmt55/p54 nrbprotein detection with polyclonal antibody NMT-4 is a point mutation in the epitope for polyclonal antibody NMT-4, a post-translational modification, such as phosphorylation, in or near this epitope or an alternative splice variant affecting this epitope.
Interestingly however, polyclonal antibody NMT- 4 detected nmt55/p54 nrbin only 3 out of 5 ER+ tumors.
Polyclonal antibodies were developed against these peptides; polyclonal antibody NMT-4 recognized a sequence in the amino terminal region of nmt55/p54 nrband polyclonal antibody NMT-5 recognized a sequence in a mid-region of nmt55/p54 nrb(Figure 1B).