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Example sentences for: nachbac
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There are now three families of eukaryotic ion channel genes for which only a few homologs have been identified in prokaryotes: the first family is a glutamate-activated K +channel, GluR0 [ 14 ] from Synechocystis PCC 6803, that is homologous to eukaryotic ionotrophic glutamate receptors; the second family is a Na +channel, NaChBac, from Bacillus halodurans [ 15 ] , [ 26 ] and homologous sequences from Thermobifida fusca and Magnetococcus sp.
Similarly, the fact that NaChBac is about equidistant from consensus sequences of all four 6TM motifs of eukaryotic Ca 2+channels [ 15 ] is consistent with the hypothesis that Ca 2+channels initially evolved first in prokaryotes as homotetramers from 6TM Kv-like channels and then underwent two consecutive gene duplication events to evolve into the eukaryotic Ca 2+channels that have only one pore-forming subunit that contains four consecutive 6TM motifs.