Words similar to myocyte
Example sentences for: myocyte
How can you use “myocyte” in a sentence? Here are some example sentences to help you improve your vocabulary:
The furazolidone-induced turkey model is a well characterizedexperimental model of dilated cardiomyopathy with features verysimilar to those found in human heart failure [ 19 20 21 22 ] .Decreased contractile function (reduced fractional shortening ofthe left ventricle) and morphological changes (increased heart volumes,left ventricular dilatation, and myocyte hypertrophy) are characteristic featuresof this model [ 21 22 ] .
One of the difficulties with alchemy and this new age of cardiac myocyte biology is related to defining a rigorous set of criteria that allow one to make the claim that the cell type of interest is truly a cardiac progenitor or stem cell and is acquiring a fully differentiated phenotype [4].
These observations,and the results from several animal models, demonstrate that apoptoticcells are present in failing hearts, suggesting that apoptosis mightbe a mechanism involved, at least in part, in the progression ofheart failure and the reduction of myocyte mass.
Recent studies have proposed that myocyte loss incardiomyopathy can occur by apoptosis without an inflammatory response [reviewedin [ 1 2 3 ] ]. In heart failure,growth stimulation initially occurs as a compensatory effort tomeet chronically altered hemodynamic demands and is mediated by systemicand/or local up-regulation of mediators of adrenergic pathways andby various cytokines [ 4 5 ] . However, cytokinescan be directly toxic to cardiac myocytes and result in increasedapoptotic cell death [ 3 6 ] . Local up-regulationof angiotensin II induces immediate-early genes, which may leadto increased protein synthesis and myocardial hypertrophy or, alternatively,may up-regulate expression of apoptotic proteins (such as p53) incardiac myocytes.
This provided a consistent histological section for estimates of myocyte vacuolization and toxicity.
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