Words similar to myofibroblasts
Example sentences for: myofibroblasts
How can you use “myofibroblasts” in a sentence? Here are some example sentences to help you improve your vocabulary:
When grown in vitro keloid fibroblast cultures contain a high percentage of α-smooth muscle actin (α-SMA) expressing cells - myofibroblasts.
Cellular FN is abundantly present in granulation tissue, is produced primarily by the wound fibroblasts and myofibroblasts.
Progression of granulation tissue to neodermis requires a decrease in cellularity through apoptosis of endothelial cells, fibroblasts and myofibroblasts [ 28 29 ] . Keloid fibroblasts demonstrate aberrant apoptotic behavior [ 30 31 ] although studies have given variable results [ 5 9 11 30 31 32 33 34 35 ] . Our initial data for serum-starvation-induced apoptosis in monolayer cultures of dermal fibroblasts demonstrated delayed apoptosis of keloid fibroblasts and a negative correlation with α-SMA expression [ 36 ] . Similar correlations were observed in rat lung fibroblasts, where TGFβ1 increased α-SMA content while acting as an antiapoptotic agent [ 37 38 ] . It should be noted however, that many of the myofibroblasts were still able to undergo apoptosis consistent with in vivo data on palatal wound healing [ 39 ] . Thus, TGFβ1 can promote both α-SMA expression in the initial stages of wound healing and apoptosis in later stages of wound healing.
However, during granulation tissue remodeling in vivo, decreased cellularity may be the result of apoptosis of fibroblasts and myofibroblasts [ 29 ] .
The decrease in percentage of myofibroblasts in the relaxed gels containing keloid fibroblasts (compare Fig.