Words similar to myofibroblasts
Example sentences for: myofibroblasts
How can you use “myofibroblasts” in a sentence? Here are some example sentences to help you improve your vocabulary:
Progression of granulation tissue to neodermis requires a decrease in cellularity through apoptosis of endothelial cells, fibroblasts and myofibroblasts [ 28 29 ] . Keloid fibroblasts demonstrate aberrant apoptotic behavior [ 30 31 ] although studies have given variable results [ 5 9 11 30 31 32 33 34 35 ] . Our initial data for serum-starvation-induced apoptosis in monolayer cultures of dermal fibroblasts demonstrated delayed apoptosis of keloid fibroblasts and a negative correlation with α-SMA expression [ 36 ] . Similar correlations were observed in rat lung fibroblasts, where TGFβ1 increased α-SMA content while acting as an antiapoptotic agent [ 37 38 ] . It should be noted however, that many of the myofibroblasts were still able to undergo apoptosis consistent with in vivo data on palatal wound healing [ 39 ] . Thus, TGFβ1 can promote both α-SMA expression in the initial stages of wound healing and apoptosis in later stages of wound healing.
We utilized monoclonal antibody specific for α-SMA, a marker for myofibroblast cells, and found that neointima seen in the aortas of MCMV infected experimental animals contained myofibroblasts.
4are the four classes of fibroblasts which could be distinguished: α-SMA -, apoptosis -(lower left quadrant LL, "naïve" fibroblasts); α-SMA +, apoptosis -(upper left quadrant UL, myofibroblasts); α-SMA -, apoptosis +(lower right quadrant LR, apoptotic fibroblasts) and α-SMA +, apoptosis +(upper right quadrant UR, apoptotic myofibroblasts).
To determine the extent to which the myofibroblast phenotype is expressed and the extent to which myofibroblasts undergo apoptosis, α-SMA content and apoptosis were measured simultaneously using two-color FACS analyses.
Myofibroblasts are rich in F-actin bundles, which establish cell-cell and cell-matrix linkages and thus generate the force for wound contraction.
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