Words similar to myofibroblasts
Example sentences for: myofibroblasts
How can you use “myofibroblasts” in a sentence? Here are some example sentences to help you improve your vocabulary:
Some of the fibroblasts differentiate into myofibroblasts, which contract to close the wound [ 4 14 15 ] . Myofibroblasts are fibrogenic, showing elevated expression of interstitial collagens, laminin, FN and TN, and inhibitors of matrix metalloproteinases such as TIMP-1 [ 15 16 17 18 19 ] . Because cCAF is expressed highly in the granulation tissue of wounds in areas where ECM is abundant [ 3 6 11 ] , and it stimulates fibroblasts to differentiate into myofibroblasts [ 4 ] , we investigated whether this chemokine stimulates the production of the four major ECM molecules mentioned above, interstitial Colls I and III, TN and cellular FN.
This dose of cCAF was chosen because it was the optimal dose for inducing differentiation of myofibroblasts, cells known to produce large amounts of ECM [ 4 ] . Media was changed and new cCAF or peptides added every day for 4 days.
In order to follow both the differentiation of fibroblasts into myofibroblasts and their apoptosis in relation to the tension in the surrounding ECM, we utilized two-color FACS analyses.
Cellular FN is abundantly present in granulation tissue, is produced primarily by the wound fibroblasts and myofibroblasts.
4are the four classes of fibroblasts which could be distinguished: α-SMA -, apoptosis -(lower left quadrant LL, "naïve" fibroblasts); α-SMA +, apoptosis -(upper left quadrant UL, myofibroblasts); α-SMA -, apoptosis +(lower right quadrant LR, apoptotic fibroblasts) and α-SMA +, apoptosis +(upper right quadrant UR, apoptotic myofibroblasts).
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