Example sentences for: myofibroblasts

How can you use “myofibroblasts” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We utilized monoclonal antibody specific for α-SMA, a marker for myofibroblast cells, and found that neointima seen in the aortas of MCMV infected experimental animals contained myofibroblasts.

  • It had a pro-apoptotic effect on myofibroblasts.

  • TGFβ1 also supports the differentiation of fibroblasts into myofibroblasts, which are a major constituent of the granulation tissue [ 23 24 ] . The process depends upon the deformability of the ECM [ 17 25 ] and is mediated by the ED-A splice variant of fibronectin [ 26 27 ] . ED-A fibronectin is expressed in the initial stages of wound healing and along with collagen I is positively regulated by TGFβ1 [ 26 ] .

  • However, during granulation tissue remodeling in vivo, decreased cellularity may be the result of apoptosis of fibroblasts and myofibroblasts [ 29 ] .

  • This is consistent with other data on gel-embedded foreskin fibroblasts, which led to the conclusion that prior differentiation into myofibroblasts is not required for apoptosis in granulation tissue [ 41 ] . Our data on attached gels (when α-SMA positive fibroblasts were present even without exogenous TGFβ1) demonstrated that a considerable percentage of myofibroblasts underwent apoptosis (Fig.


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