Words similar to myofibroblasts
Example sentences for: myofibroblasts
How can you use “myofibroblasts” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the granulation tissue of burn wounds, expression of groα /MGSA and CXCR2 (the receptor for MGSA) was associated with fibroblasts, smooth muscle cells/myofibroblasts and a subpopulation of macrophages [ 7 ] . Groα/MGSA and IL-8 have also been shown to enhance re-epithelialization of human skin grafts in chimeric mice [ 29 38 ] . It has also been found that several CXC chemokines can modulate angiogenesis [ 39 ] , a process that is critical for proper healing.
It had a pro-apoptotic effect on myofibroblasts.
Some of the fibroblasts differentiate into myofibroblasts, which contract to close the wound [ 4 14 15 ] . Myofibroblasts are fibrogenic, showing elevated expression of interstitial collagens, laminin, FN and TN, and inhibitors of matrix metalloproteinases such as TIMP-1 [ 15 16 17 18 19 ] . Because cCAF is expressed highly in the granulation tissue of wounds in areas where ECM is abundant [ 3 6 11 ] , and it stimulates fibroblasts to differentiate into myofibroblasts [ 4 ] , we investigated whether this chemokine stimulates the production of the four major ECM molecules mentioned above, interstitial Colls I and III, TN and cellular FN.
This dose of cCAF was chosen because it was the optimal dose for inducing differentiation of myofibroblasts, cells known to produce large amounts of ECM [ 4 ] . Media was changed and new cCAF or peptides added every day for 4 days.
reduction of tension in the ECM provokes apoptosis and reduces α-SMA; as human dermal myofibroblasts readily undergo apoptosis in response to gel relaxation (or wound contraction) their absence from the neodermis of a healed wound is likely the result of apoptosis.
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