Words similar to myofibroblasts

Example sentences for: myofibroblasts

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The decrease in percentage of myofibroblasts in the relaxed gels containing keloid fibroblasts (compare Fig.
In adults, TN, specifically TN C, is present almost exclusively in the granulation tissue of healing wounds [ 12 24 ] . In addition to providing a matrix for rapid migration of cells during wound repair, TN supports differentiation of fibroblasts into myofibroblasts [ 25 ] , which then produce more TN than do normal fibroblasts [ 15 18 ] . Because cCAF stimulates fibroblasts to differentiate into myofibroblasts, we tested the possibility that this chemokine also affects TN production.
To determine the extent to which the myofibroblast phenotype is expressed and the extent to which myofibroblasts undergo apoptosis, α-SMA content and apoptosis were measured simultaneously using two-color FACS analyses.
We showed previously that cCAF is highly expressed in the granulation tissue of wounds [ 6 36 ] , that this chemokine and several of its human homologues stimulate differentiation of fibroblasts into myofibroblasts both in culture and in vivo, and that the latter effect can be achieved very effectively by the N-terminal 15aas of the protein [ 4 37 ] . In addition to cCAF, other CXC chemokines have been associated with wound healing events.
These data taken together strongly suggest that as chemokines induce the differentiation of fibroblasts into myofibroblasts they contribute to the production of TN in the granulation tissue.