Example sentences for: myofilament

How can you use “myofilament” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Nevertheless, these results illustrate the importance of calcium handling in the energetic efficiency of an inotrope, and these methods will be useful in studying genetically engineered mouse models with altered myofilament calcium responsiveness.

  • In the perfused mouse heart, high perfusate calcium positive inotropy compared to dobutamine results in reduced myofilament calcium responsiveness, decreased energetic efficiency and is dependent in part on protein kinase C activation.

  • Also, indicating reduced myofilament responsiveness to perfusate calcium 3.5 mM compared to dobutamine, levels of peak intracellular calcium were similar for these 2 interventions despite higher developed pressure with dobutamine.

  • Peak systolic intracellular calcium increased minimally between 1.5 and 2.5 mM despite significant increases in developed pressures indicating increased myofilament responsiveness to calcium at perfusate calcium 2.5 compared to 1.5 mM (Figure 1B).


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