Words similar to myoc

Example sentences for: myoc

How can you use “myoc” in a sentence? Here are some example sentences to help you improve your vocabulary:

PCR and processing were as described above with the exception that the 5' human MYOC deletion products were cloned into a HindIII/Bsu36I digested pcDNA3.hMYOC wild-type vector.
Cloning of rabbit MYOC
Due to difficulties in amplifying the rabbit MYOC coding region from cDNA, we pieced together the entire contiguous open-reading frame using rabbit genomic DNA (Clontech; New Zealand White) as a template with a multi-step PCR/ligation process.
However, an extensive study of mutations in the proximal promoter and coding region of MYOC found no sequence polymorphisms associated with steroid responsiveness [ 15 ] .
Mutations in MYOC have been shown to be causative for primary open angle glaucoma (POAG) [ 1 2 3 ] . Glucocorticoids have been implicated in ocular hypertension and glaucoma due to increased plasma cortisol levels [ 4 5 ] and altered cortisol metabolism [ 6 7 ] in POAG patients and from the increased risk of developing POAG in steroid-responsive patients [ 8 9 ] . Myocilin has been shown to be upregulated in glucocorticoid-treated human trabecular meshwork (TM) cells [ 10 11 ] , and there is variable evidence for increased MYOC expression in glaucomatous individuals [ 12 13 14 ] . In addition, glaucoma patients have a higher chance of responding to steroids than non-glaucomatous individuals.