Words similar to monomeric
Example sentences for: monomeric
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Endogenous HsCOP1 was found to accumulate primarily in large complexes of over 700 kDa, whereas no monomeric or dimeric form of HsCOP1 was detected (Fig 4).
Biochemical reconstitution studies using purified recombinant actin in vitro and studies in RSV-infected cells ( ex vivo ) demonstrated that actin functions as a viral transcription factor in both monomeric (G) and filamentous (F) forms, whereas the filamentous form appeared to be particularly important for viral morphogenesis [ 10 ] . Subsequent studies showed that at saturating actin concentration, profilin stimulated viral transcription even further, whereas profilin by itself had no transcriptional activity in the absence of actin [ 11 ] . These results suggested that the interaction of profilin with actin may be important for optimal activity of the RSV transcriptase.
The trans-silencers as well as their targets reside in single-copy, gene-rich regions that are only sparsely populated with repetitive or transposable elements, features that have been shown to mediate epigenetic activity in other cases [ 18 31 32 ] . Therefore trans-silencing of GFP-COP1 is probably not mediated by transgene flanking sequences [ 27 ] . In contrast, as with other genes cited above, trans-silencing ability is correlated with transgene locus structure, given that the C73 and C97 trans-silencers contain multiple T-DNAs while their targets, E82 and L91, are essentially dimeric and monomeric, respectively.
When the protein is fully phosphorylated, it remains largely in the monomeric state; whereas removal of these phosphates allows the protein to assemble into thick filaments.
A similar epigenetic instability of the initial PTGS phenotype was typical for a subset of other oligomeric loci, but was never observed with monomeric 35S:GFP-COP1 loci.
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