Words similar to monomeric
Example sentences for: monomeric
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Under these conditions, moesin and β-actin migrated predominantly as monomeric polypeptides at 45 and 78 kDa positions on the SDS-PAGE gels and only very small amounts of crosslinked moesin and β-actin were detected by western blotting at higher molecular weight positions (data not shown).
The results shown in Figure 1A, indicate that the sedimentation peak for the wild type p66/p66 homodimer was between fractions 16-19 of the gradient (Panel A), whereas the wild type p51 species sedimented between fractions 22-28, as a monomeric protein (Panel C).
A similar epigenetic instability of the initial PTGS phenotype was typical for a subset of other oligomeric loci, but was never observed with monomeric 35S:GFP-COP1 loci.
The ability of soluble monomeric G-actin to polymerize into filamentous F-actin in a reversible manner is central to the cellular function of actin [ 1 2 ] . Rearrangement of actin is promoted rapidly by extracellular stimuli, and is facilitated by sets of actin-associated proteins, one of which is profilin [ 2 ] . It is now appreciated that a large number of cellular parasites co-opt actin for their gene expression and replication in the host cell [ 3 4 ] . Due to its primary role in pediatric respiratory disease, and the enormous human and economic toll it exacts throughout the world, the respiratory syncytial virus (RSV) and its interaction with the host cell have received serious attention.
Crystal structures of HIV-1 RT show that p66 and p51 assume different folding patterns and tertiary structures [ 11 12 ] . It has been proposed that p66 in a monomeric form exists in a closed conformation similar to p51 [ 26 ] . Following dimerization with another molecule of p51 (or p66), it assumes an open conformation [ 11 14 15 ] . The polymerase domain of p51 is buried within its core.
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