Words similar to monomer
Example sentences for: monomer
How can you use “monomer” in a sentence? Here are some example sentences to help you improve your vocabulary:
The burial of positively selected variants in the gp120 monomer confirms that gp120 quasispeciation is not selected solely for escape from B-cell immunity.
As shown in Figure 6C(second and third lanes), the addition of these compounds for 1 hr to the solution bathing the oocytes and to the homogenization solution did not modify the monomer:dimer ratio when compared to the control lane (p > 0.05, for 3 independent experiments).
Distinct nAChR subtypes exist that can be stimulated by the neurotransmitter acetylcholine, the natural product nicotine, or by synthetic compounds [ 1 ] . nAChR is the prototype for a protein superfamily that includes the receptors for the excitatory amino acids glutamate and aspartate, the inhibitory amino-acids gamma-aminobutyric acid (GABA) and glycine, as well as the serotonin 5-HT 3 receptor [ 1 ] . Like most ligand-gated ion channels, nAChRs are homo- or hetero-pentameric, each monomer belonging to a pull of 8 alpha- or 3 beta-subunits (alpha 2-9 , beta 2-4 ). While each subunit has four transmembrane domains, the agonist binding sites are located at the subunit interfaces [ 2 ] . Both natural and synthetic ligands can display varied affinity for different receptor subtypes.
A disulfide bridge (the so-called cys-loop), present only in the alpha subunits of nAChR, is known to be part of the agonist binding site of the receptor [ 7 ] . This was a clear indication that, in order to build a dimer interface that includes the ligand binding pocket, alpha subunits had to be aligned onto the template monomer presenting a disulfide bridge at the interface (subunit 1).
The crystal structure of nucleotide-bound forms of rabbit Hint showed that the carboxy-terminal amino acids of each Hint monomer extend across the dimer interface and are buried near the opposing nucleotide.
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