Words similar to mononuclear

Example sentences for: mononuclear

How can you use “mononuclear” in a sentence? Here are some example sentences to help you improve your vocabulary:

The reasons for IL10 production by mononuclear cells in NSCLC are speculative and may be varied.
Diagnostic Peripheral Blood Mononuclear Cell Gene Expression Signatures
It was shown in rats that binuclear hepatocytes have double the volume of mononuclear hepatocytes and that the extrahepatocytic space volume was 15% of the total liver volume [ 10 ] .
The selective suppression of Th1 cell activity is believed to be due to IL-10 inhibition of IL-12, a differentiation factor for Th1 cells [ 11 12 ] . The release of reactive oxygen and nitrogen intermediates by macrophages is also suppressed by IL-10 [ 13 14 ] . In addition, IL-10 stimulates the production of cytokine inhibitors such as IL-1 receptor antagonist [ 15 ] . In patients with rheumatoid arthritis, IL-10 is produced by synovial membrane cells and is found at high levels in the synovial fluid [ 16 17 ] . It has been shown that suppression of IL-10 production by synovial cells is associated with increased levels of IL-1 and TNF-α, suggesting that IL-10 plays a suppressive role in rheumatoid arthritis joints [ 16 ] . It was also observed that IL-10 directly stimulated proteoglycan synthesis and reversed the cartilage degradation induced by activated mononuclear cells [ 18 ] . These immunosuppressive activities indicate that IL-10 is a potential therapeutic approach for autoimmune diseases.
Peripheral blood mononuclear cells were isolated from whole blood of healthy donors following apheresis and elutriation.