Example sentences for: mononuclear

How can you use “mononuclear” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The cause of SSc is unknown but the early stage is characterized by a dense mononuclear cell infiltrate in tissues, suggesting that activation of the immune system results in the development of tissue fibrosis [ 3, 4].

  • The ability of Mycobacterium tuberculosis bacteria to infect and replicate inside host mononuclear phagocytes is key to its ability to establish an infection and cause tuberculosis.

  • The mononuclear cells were isolated from the supernatant containing dissociated cells by Percoll gradient centrifugation.

  • Yet, elevated maternal mid-trimester chorionic gonadotropin is associated with fetal cerebral blood flow redistribution and adverse perinatal outcome [ 63 ] . In addition, estrogens, which are known to cause a diminution of high LH levels in postmenopausal women, have been reported to be effective in the prevention and treatment of Alzheimer's disease [ 72 73 74 ] . Microglia belong among cells of the mononuclear phagocyte system [ 75 ] . Since CG increases secretion of a variety of cytokines by monocytes, and induces their inflammatory reaction and phagocytic activity [ 76 77 78 79 ] , high LH levels in aging individuals may also activate resident macrophages in the central nervous system and contribute to the development of Alzheimer's disease and other inflammation-mediated neurodegenerative diseases.

  • This has been referred to as the LAK phenomenon [ 1 ] . Similarly IL-12 treatment of peripheral blood mononuclear cells (PBMC) or pure NK cells within a few hours, induces, an enhancement of cytotoxic ability.


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