Example sentences for: mitogenic

How can you use “mitogenic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Ras/MAPK pathway is typically thought to be a part of a mitogenic pathway [ 36 ] . However, we and others have shown that prolonged treatment with III1-C can inhibit cell proliferation [ 3 4 ] , and here we show that cell adhesion to III1-C can activate ERK1/2.

  • Based on the observations that TCF factors as well as p35-C/EBPβ: (1) interact with SRF (2) transactivate the SRE and (3) are responsive to Ras-dependent signaling pathways, we tested the possibility that both TCF and p35-C/EBPβ are necessary for maximal induction of the SRE in response to mitogenic stimulation.

  • VEGF is a dimeric glycoprotein and has specific mitogenic activity for endothelial cells.

  • The lack of aberrant neuronal proliferation in our mice suggests that differentiated neurons may not be as susceptible to the mitogenic effects of Wnt signaling as are neuroepithelial progenitor cells [ 22 ] .

  • eIF4E gene transcription is enhanced in response to mitogenic stimulation and may be mediated by c-myc [ 3 ] . Phosphorylation of eIF4E by the protein kinase Mnk1 increases its affinity for the cap, and thus increases cap-dependent initiation of translation [ 4 5 6 ] . An inhibitor of eIF4E, 4E binding protein (4EBP), is also regulated by phosphorylation.


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