Example sentences for: mgmt

How can you use “mgmt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Of note, the MGMT gene exhibited down-regulated expression in 22 of the 23 (95.

  • See Reg'l Mgmt.

  • These data, therefore, rule out the possibility that not all tumors arising from embryonic-type cells show down-regulated expression of MGMT .

  • MGMT gene encodes O(6)-methylguanine-DNA methyltransferase and this enzyme effectively removes DNA adducts formed by alkylating agents [ 33 ] . Epigenetic gene silencing of MGMT confers enhanced sensitivity to alkylating-based chemotherapy, and lack of methylation associates with failure to respond to chemotherapy [ 34 35 ] . On the contrary, all patients that had MGMT promoter methylation were dead within 21 months of initial diagnosis, which predicts a poor prognosis.

  • The data also suggest that multiple mechanisms, in addition to the promoter methylation, may play a role in silencing of MGMT gene expression in GCTs of all histologic subsets.


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