Example sentences for: mgmt

How can you use “mgmt” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although the patterns are similar, primary tumors had a higher frequency of methylation of CDH1 and DAPK genes as compared to cell lines, while RARB , HIC1 , RASSF1A , MGMT , and TP73 genes had higher prevalence in cell lines as compared to primary tumors (Table 1).

  • These data, therefore, rule out the possibility that not all tumors arising from embryonic-type cells show down-regulated expression of MGMT .

  • However, methylation of 3 genes did suggest a doubling ( RASSF1A and MGMT ) or tripling ( BRCA1 ) of risk compared to those who did not have these genes methylated.

  • Our current observation that undetectable levels of MGMT gene expression in >95% of GCTs appears to suggest that the lack of the O(6)-methylguanine-DNA methyltransferase enzyme may direct cells to undergo apoptosis due to failure of repair of DNA adducts formed by alkylating agents.

  • In this group, all the patients that showed methylation of MGMT and BRCA1 genes failed to respond to the treatment suggesting promoter methylation of these genes may be a bad prognostic indicator (Table 2).


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