Words similar to mgsa
Example sentences for: mgsa
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In addition to MCP-1, IL-8 and MGSA have also been evaluated for production of collagen [ 46 ] . These investigators reported that treatment of normal fibroblasts with these chemokines did not affect collagen levels.
In the granulation tissue of burn wounds, expression of groα /MGSA and CXCR2 (the receptor for MGSA) was associated with fibroblasts, smooth muscle cells/myofibroblasts and a subpopulation of macrophages [ 7 ] . Groα/MGSA and IL-8 have also been shown to enhance re-epithelialization of human skin grafts in chimeric mice [ 29 38 ] . It has also been found that several CXC chemokines can modulate angiogenesis [ 39 ] , a process that is critical for proper healing.
MGSA melanoma growth stimulatory activity
We have previously determined, using dose-dependent studies, that this concentration is optimal for functions of this chemokine on these embryonic fibroblasts and in processes of granulation tissue formation [ 3 4 ] ). Although chemokine concentrations of 10 -2-10 ng/ml can chemoattract and activate leukocytes, chemokines acting on other cell types such as endothelial cells, smooth muscle cells and fibroblasts require concentrations in the range of 10 2ng/ml and higher [ 4 26 27 28 ] . This is within physiological range; for example wound fluid from burn patients contain MGSA (a chemokine that is highly homologous to cCAF) concentrations of 10 2-10 3ng/ml [ 29 ] . Because both the N-terminal and C-terminal peptides of cCAF have been shown to be functional in culture and in vivo (1-4, 30), we also tested these two peptides (Fig.
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