Example sentences for: metastatic

How can you use “metastatic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our finding that TYRP-1 is also expressed in the poorly metastatic or noninvasive cell lines NM-2C5 [ 2 ] , T47D, MCF7 and DU145 [ 5 ] , which are derived from human breast cancers and prostate tumors that are nonmetastatic, indicates that this molecule is not exclusively expressed in cells of the melanocytic lineage.

  • This trial was also a randomized metastatic colorectal cancer study, comparing a new chemotherapy standard of care, 5-FU/leucovorin/CPT [ 24 25 ] to standard of care plus SU5416.

  • When analyzed by tumor stage, LOH on 18p was found in 56% (9/16) of ductal carcinoma in situ (DCIS) foci, 67% of invasive ductal carcinoma (IDC) foci (14/21), and 67% (4/6) of metastatic disease.

  • The age-related β Lform accumulates with a slightly higher kinetic rate than α DCTX [ 9 ] . This is also apparent from the less pronounced increase in the α L/β Lratio compared with the α L/α Dratio in metastatic patients.

  • This finding suggests that the expression of these proteins in breast cancer is regulated by soluble factors produced by the tumor cells [ 26 27 ] . High levels of expression of HGF and Met are associated with invasive breast cancer, and might be causally linked to early recurrences, metastatic disease and shortened survival of breast cancer patients [ 28 29 ] . High levels of HGF/SF detected within breast tumor extracts are correlated with larger tumor size and shorter relapse-free and overall survival compared with tumors with low HGF/SF concentration [ 30 ] .


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