Words similar to metastasis
Example sentences for: metastasis
How can you use “metastasis” in a sentence? Here are some example sentences to help you improve your vocabulary:
The presence or absence of bone metastasis in patients was determined by bone scintigraphy, and was confirmed by conventional radiography (X-ray) as necessary.
The epithelial component of normal and non-invasive breast tissues is normally surrounded by a layer of myoepithelial (ME) cells, whose absence or disruption is an absolute prerequisite for tumor invasion and metastasis [ 1 ] . ME cells are not easily identifiable in hematoxylin/eosin (H&E)-stained breast tissue sections, as they are often indistinguishable from subjacent myofibroblastic cells in the stroma.
Similarly, the wild-type metastasis suppressor genes regulate the cell's mobility and its response to environmental messages, presumably keeping most cells localized and differentiated.
A high percentage of node-positive primary tumors (73%), metastatic carcinomas (73% and 100% concordance between primary tumor and associated metastasis, respectively), primary carcinomas without metastases (89%), benign breast specimens (70%) and normal (60%) breast specimens were positive for TYRP-1 staining (Fig.
Mediators known to activate ECs include inflammatory cytokines, growth factors such as VEGF/VPF and basic fibroblast growth factor (bFGF), extracellular matrix (ECM) proteins such as collagen and fibronectin, and proteases such as MMPs [ 1 2 ] . In vitro and in vivo assays indicate that VEGF signaling promotes increased permeability, cell migration, proliferation, and differentiation, functioning through two EC-specific tyrosine kinase receptor such as Kinase domain receptor (KDR) [ 1 2 3 ] . In the majority of solid tumors, VEGF is upregulated in response to hypoxia, inducing the expression of pro-angiogenic genes that promote tumor angiogenesis, growth and eventual metastasis [ 3 4 5 ] . The expression of both positive and negative factors must be tightly and specifically regulated in a coordinated manner.
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