Example sentences for: metastasis

How can you use “metastasis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Met signaling can increase tumorigenicity, induce cell motility, and enhance invasiveness in vitro and metastasis in vivo [ 14 17 18 19 20 ] . In addition, Met signaling can increase the production of protease and urokinase, which are associated with extracellular matrix/basal membrane degradation and are important for metastasis [ 14 19 ] .

  • The measurement of CTX isoforms, and the ratios between the native α Lform and the age-modified forms of CTX, indicative of the age of the resorbed collagen fragments, may thus provide clinical useful information for diagnosing and monitoring bone metastasis occurrence in cancer patients [ 11 ] . Such an application of the CTX bone resorption markers may be especially relevant for breast cancer patients, who have a high risk of developing bone metastases.

  • To characterize the changes of p53, iNOS and VEGF expression in human gastric carcinogenesis, the present study was undertaken to determine the protein level of p53, iNOS and VEGF in normal tissues and the tissues with different severities of lesions of CSG, CAG, DYS, IM and GC with and without lymph node metastasis from surgically resected human GC and gastric biopsies from symptom-free subjects.

  • Isoforms B and D (AF022952 and AF014827) were positively correlated with % clear space itself, whereas isoform C (AF010302) was negatively correlated with both area % vacuoles and vacuoles/mm 2. VEGF Ch was reported to be involved in cancer metastasis and tumor-cell invasion [ 25 26 ] , whereas isoforms B and D are believed to have roles in proliferation and tissue remodeling [ 27 28 29 30 ] , highlighting the diverse roles of these cytokines.

  • avß3 integrin has a role in cell migration and extravasation, which occurs during metastasis, and also in angiogenesis—the development of new blood vessels that are essential for the growth of tumors.


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