Words similar to metazoans
Example sentences for: metazoans
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The Toll-like receptor family [ 49], which has evolutionary roots throughout invertebrate metazoans for pattern-based recognition of bacterial and fungal cell-surface components [ 50], activate NFκB through convergent pathways involving the IL-1 receptor-associated kinase (IRAK), the adaptor protein MyD88, TRAF6, NFκB-inducing kinase (NIK), and IκB kinase (Iκk) [ 51].
Gene products in this category are generally widely conserved across metazoans and many are involved in core biological processes.
The generation of expressed sequence tags (ESTs) by single-pass random sequencing of cDNA libraries is a powerful tool for rapid gene transcript identification in metazoans [ 14 15 16 17 ] including parasitic nematodes of humans and animals [ 18 19 20 21 22 23 ] . High-throughput projects on two dozen nematode species have now brought the total number of publicly available roundworm ESTs to nearly 400,000, with half the sequences coming from parasites [ 24 25 26 27 ] . As a part of these efforts, EST sequencing from plant parasitic nematodes is in progress [ 28 ] and pilot EST datasets from the root-knot nematode M. incognita and the cyst nematodes Globodera rostochiensis and G. pallida second-stage larvae have recently been analyzed [ 29 30 ] .
The transcription factor E2F is an important regulator of the G1/S phase transition in metazoans and a major target of the tumor suppressor Rb [ 10 ] [ 11 ] . The mechanisms controlling E2F activity have not been completely elucidated.
Runx sequences from lophotrochozoans and from basal (non-bilaterian) metazoans (e.g.
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