Words similar to metazocine
Example sentences for: metazocine
How can you use “metazocine” in a sentence? Here are some example sentences to help you improve your vocabulary:
Louis, MO), nalbuphine and β-endorphin were obtained from RBI (Natik, MA), cyclazocine, etorphine, metazocine, morphine, nalorphine, and SKF 10047 were obtained from National Institute of Drug Abuse (Bethesda, MD), lofentanil was from Janssen Pharmaceutical Inc. (Titusville, NJ), Dezocine was from Wyeth Laboratories (Philadelphia, PA), Win 444,441 was from Sterling Winthrop Pharmaceutical and Xorphanol was from Miles Inc.
The only exceptions were the highly efficacious ligands fentanyl (P < 0.05), metazocine (P < 0.001) and xorphanol (p < 0.001).
Thus the present study was designed, (1) to describe the activation profiles of a set of opioid ligands not previously defined at an isolated cell system expressing only δ opioid receptors, and (2) to compare the relative efficacies and potencies of these ligands to the strongest ligand in the set, metazocine, to the common opioid analgesic, morphine and to the endogenous δ opioid ligand, met-enkephalin.
The rank order of potency of the drugs studied were; etorphine > hydromorphone > dezocine > xorphanol = nalorphine = butorphanol = lofentanil > metazocine > nalbuphine > cyclazocine > fentanyl > morphine >>>> β-endorphin.
Maximal inhibitory effect of each ligand was compared to the levels of maximal inhibition by met-enkephalin, metazocine and morphine using ANOVA analysis with Dunnett's multiple comparison as post test using PRISM software (GraphPad Software, Inc.