Example sentences for: metazocine

How can you use “metazocine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The other ligands, met-enkephalin, WIN 44,441, hydromorphone and Butorphanol, exhibited potencies of 10-100 nM; metazocine and SKF 10047, 100-200 nM, and nalbuphine, dezocine and morphine, 400-1000 nM.

  • The only exceptions were the highly efficacious ligands fentanyl (P < 0.05), metazocine (P < 0.001) and xorphanol (p < 0.001).

  • Thus the present study was designed, (1) to describe the activation profiles of a set of opioid ligands not previously defined at an isolated cell system expressing only δ opioid receptors, and (2) to compare the relative efficacies and potencies of these ligands to the strongest ligand in the set, metazocine, to the common opioid analgesic, morphine and to the endogenous δ opioid ligand, met-enkephalin.

  • The rank order of efficacy of the ligands tested was metazocine = xorphanol ≥ fentanyl = SKF 10047 = etorphine = hydromorphone = butorphanol = lofentanil > WIN 44,441 = Nalbuphine = cyclazocine ≥ met-enkephalin >> morphine = dezocine.

  • Louis, MO), nalbuphine and β-endorphin were obtained from RBI (Natik, MA), cyclazocine, etorphine, metazocine, morphine, nalorphine, and SKF 10047 were obtained from National Institute of Drug Abuse (Bethesda, MD), lofentanil was from Janssen Pharmaceutical Inc. (Titusville, NJ), Dezocine was from Wyeth Laboratories (Philadelphia, PA), Win 444,441 was from Sterling Winthrop Pharmaceutical and Xorphanol was from Miles Inc.


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