Example sentences for: metazocine

How can you use “metazocine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Louis, MO), nalbuphine and met-enkephalin were obtained from RBI (Natik, MA), cyclazocine, etorphine, metazocine, morphine, nalorphine, and SKF 10047 were obtained from National Institute of Drug Abuse (Bethesda, MD), lofentanil was obtained from Janssen Pharmaceutical Inc. (Titusville, NJ), Dezocine was obtained from Wyeth Laboratories (Philadelphia, PA), Win 444,441 was obtained from Sterling Winthrop Pharmaceutical and Xorphanol was obtained from Miles Inc.

  • Finally the four weakest agonists, cyclazocine, dezocine, metazocine and xorphanol all exhibited efficacies that showed statistically significant difference when compared to fentanyl (p < 0.01), and thus were categorized as partial agonists.

  • The rank order of potency of these ligands was; etorphine>lofentanil≥cyclazocine=xorphanol>met-enkephalin> Win 44,441=hydromorphone≥butorphanol>metazocine=SKF 10047> dezocine≥ nalbuphine>morphine>fentanyl.

  • Moreover, fentanyl, metazocine and xorphanol could be considered "super agonists" at delta receptors based on having efficacies significantly greater than met-enkephalin.

  • The rank order of potency of the drugs studied were; etorphine > hydromorphone > dezocine > xorphanol = nalorphine = butorphanol = lofentanil > metazocine > nalbuphine > cyclazocine > fentanyl > morphine >>>> β-endorphin.


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