Words similar to metastasize
Example sentences for: metastasize
How can you use “metastasize” in a sentence? Here are some example sentences to help you improve your vocabulary:
There would also be considerable benefit to the 87% of women with mammary carcinomas who are not likely to metastasize by sparing them the physical, mental and financial costs of the treatment.
What holds cells together or connects them with the extracellular matrix—and what happens when these interactions break down—is one of the keys to determining how tumors metastasize.
Breast cancer cells frequently metastasize to bone causing bone destruction and hypercalcemia [ 9 ] . Parathyroid hormone-related protein (PTHrP), secreted by these cells, is a major mediator of the osteolytic process [ 10 ] . Osteolysis leads to the release of TGFβ which, in turn, further induces PTHrP expression [ 11 ] . Other tumor-relevant genes, such as pai-1 or upa , can also be activated by TGFβ.
Since Pten mutations are usually found in advanced tumors, and the protein has been suggested to inhibit cell spreading, migration, and invasion [ 36, 37], it is possible that the tumors from Wnt-1 TG, Pten +/- mice may have a higher potential to metastasize than those from mice carrying a Wnt-1 transgene in a wild type Pten background.
This suggests that even small and seemingly resectable lung cancers metastasize early.