Words similar to metalloproteinases
Example sentences for: metalloproteinases
How can you use “metalloproteinases” in a sentence? Here are some example sentences to help you improve your vocabulary:
Serum levels of the metalloproteinases and their inhibitors in patients with early synovitis
This example illustrates how functional relationships that could not be deduced from gene names were uncovered through the analysis of patterns of term occurrence: matrix metalloproteinases (MMP1, 10, 14) and urokinase plasminogen activator (UPA, SPARC) are matrix-interacting molecules involved in tumor invasion and metastasis.
Immunoblot analysis of metalloproteinases
For instance, IL-1-degraded cartilage tissues and cell suspensions are frequently employed as model systems to study cartilage metabolism under osteoarthritis-like conditions [ 1 2 3 4 ] and to assess the efficacy of various drug therapies [ 5 6 7 8 9 ] . IL-1 signals cells via cell surface receptors to upregulate proteases, matrix metalloproteinases and aggrecanase, while downregulating matrix metalloproteinase inhibition and proteoglycan synthesis [ 10 11 ] . The ultimate effect of these metabolic changes include damage to the ECM, loss of ECM components (especially proteoglycan), and alteration of the normal balance of catabolic and anabolic processes that regulate cartilage ECM composition.
EC, endothelial cell; MMP, matrix metalloproteinases; 3D, three-dimensional; KDR, kinase domain receptor; SSHDD, suppression subtractive hybridization followed by differential display; VE-cadherin, vascular endothelial-cadherin; PMA, phorbol 12-myristate 13-acetate; VEGF, vascular endothelial growth factor; bFGF, basic fibroblast growth factor.
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