Words similar to metalloproteinases
Example sentences for: metalloproteinases
How can you use “metalloproteinases” in a sentence? Here are some example sentences to help you improve your vocabulary:
Matrix metalloproteinases (MMPs) are responsible for modification of the extracellular matrix and are involved in wound healing, tumorigenesis, pregnancy and inflammation.
Some of the fibroblasts differentiate into myofibroblasts, which contract to close the wound [ 4 14 15 ] . Myofibroblasts are fibrogenic, showing elevated expression of interstitial collagens, laminin, FN and TN, and inhibitors of matrix metalloproteinases such as TIMP-1 [ 15 16 17 18 19 ] . Because cCAF is expressed highly in the granulation tissue of wounds in areas where ECM is abundant [ 3 6 11 ] , and it stimulates fibroblasts to differentiate into myofibroblasts [ 4 ] , we investigated whether this chemokine stimulates the production of the four major ECM molecules mentioned above, interstitial Colls I and III, TN and cellular FN.
These compounds may have played a role in the inhibitory effect observed, probably owing to the chelation of the zinc required for the catalytic activity of venom's haemorrhagic metalloproteinases [ 45 ] . Reduction in the intensity of the effects of envenomation could also be achieved by a neutralisation of the venom peptides, polypeptides, proteins and enzymes [ 38 11 ] . There are plants used for snakebite that act by inhibiting the proteolytic activities of the venom and antagonising crotoxin-induced haemolysis, myotoxic and haemorrhagic activities of crotalid venoms [ 46 ] .
EC, endothelial cell; MMP, matrix metalloproteinases; 3D, three-dimensional; KDR, kinase domain receptor; SSHDD, suppression subtractive hybridization followed by differential display; VE-cadherin, vascular endothelial-cadherin; PMA, phorbol 12-myristate 13-acetate; VEGF, vascular endothelial growth factor; bFGF, basic fibroblast growth factor.
The internal elastic lamella of arteries is shown to form gaps prior to vessel dilatation in an experimental arteriovenous model in rabbit carotid artery [ 2 ] . Collagenase and matrix metalloproteinases (MMPs) have been observed to be upregulated during vessel dilation either in flow-induced model [ 10 ] or in a post-stenotic dilatation [ 11 ] .
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