Words similar to mek
Example sentences for: mek
How can you use “mek” in a sentence? Here are some example sentences to help you improve your vocabulary:
The results shown here demonstrate that inhibition of MEK with U0126 quantitatively inhibits both ERK phosphorylation and AA release in MDCK cells in response to [Ca 2+] i mobilization.
Virus infectivity can be enhanced by treatment of cells with MAPK stimulators, such as serum and phorbol myristate acetate, as well as by coexpression of constitutively activated Ras, Raf, or MEK in the absence of extracellular stimulation [ 61 ] . Also, following infection, efficient disengagement of the reverse transcription complex from the cell membrane and subsequent nuclear translocation, requires phosphorylation of the reverse transcription complex components by ERK/MAPK; demonstrating a critical regulation of an early step in HIV-1 infection by the host cell MAPK signal transduction pathway [ 62 ] . Therefore, Tat down-regulation of the MAPK pathway in latent cells implies that much of the host signal transductions connected to activation are down-regulated, and at the same time, these cells may be refractory to subsequent infection by other viruses.
In addition, using cells expressing wild-type cPLA 2 and cPLA 2 with S505A or S727A mutations, it was found that translocation kinetics and membrane targeting in response to ATP or ionomycin was similar to wild-type cPLA 2 . These data suggest that MEK1 inhibition reduces cPLA 2 catalytic activity and AA release independently of phosphorylation and translocation.
Na some kine ting meka na WHISSSSH lika na shanake foh one dahk konna, he explained aggrieved, I go put fiah mek I look am gooh.
cPLA 2 translocates primarily to Golgi in response to a transient [Ca 2+] i changes and to Golgi and ER in response to a sustained [Ca 2+] i increase [ 15 ] . The reduction in AA release by MEK inhibition did not involve a failure in [Ca 2+] i release or translocation.
Loading...