Words similar to mek
Example sentences for: mek
How can you use “mek” in a sentence? Here are some example sentences to help you improve your vocabulary:
[Ca 2+] iincrease is independent of MEK1/ERK pathway
We next explored the possibility that the MEK1/2 inhibitor PD98059 and the Rho-associated kinase inhibitor Y-27632 might also interfere with Smad3 nuclear entry.
Treatment of MDCK cells with 30 μM PD098059, a less potent inhibitor of MEK [ 28 29 ] , resulted in a ~50% reduction in AA release in response to 100 μM ATP, 1 μM IONO, and 10 μM IONO (data not shown).
This MAPK pathway encompasses a cascade of phosphorylation events involving three key kinases, namely Raf, MEK (MAP kinase kinase) and ERK (MAP kinase).
Although the alternative mechanism whereby the MEK1/ERK pathway regulates cPLA 2 is not known, it is possible that it affects membrane properties and/or cPLA 2 conformation that promotes optimal hydrolytic activity.