Example sentences for: mek

How can you use “mek” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [Ca 2+] iincrease is independent of MEK1/ERK pathway

  • We next explored the possibility that the MEK1/2 inhibitor PD98059 and the Rho-associated kinase inhibitor Y-27632 might also interfere with Smad3 nuclear entry.

  • Treatment of MDCK cells with 30 μM PD098059, a less potent inhibitor of MEK [ 28 29 ] , resulted in a ~50% reduction in AA release in response to 100 μM ATP, 1 μM IONO, and 10 μM IONO (data not shown).

  • This MAPK pathway encompasses a cascade of phosphorylation events involving three key kinases, namely Raf, MEK (MAP kinase kinase) and ERK (MAP kinase).

  • Although the alternative mechanism whereby the MEK1/ERK pathway regulates cPLA 2 is not known, it is possible that it affects membrane properties and/or cPLA 2 conformation that promotes optimal hydrolytic activity.


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