Words similar to mda-mb-

Example sentences for: mda-mb-

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In order to generalize the integrin mediated TGFβ 1 -pathway identified in the SMAD4 deleted pancreatic tumor cell line BxPC-3, we investigated TGFβ 1 signaling in the cervical carcinoma cell line HeLa and the mammary carcinoma cell lines MCF-7 and MDA-MB-231, harboring a wildtype SMAD4-gene.
The study reported on here was originally designed to test the ability of a high dietary dose of sE to prevent lipid peroxidation in nude mice bearing a human breast cancer xenograft MDA-MB-231 [ 11 12 ] . To assure suppression of lipid peroxidation, sE was added to the diet at a dose level.
In order to test whether TGFβ 1 signaling via α V β 6 is specific for SMAD4 deleted BxPC-3 cells or if this is a general phenomenon, we investigated signaling in TGFβ 1 -sensitive carcinoma cell lines HeLa, MCF-7 and MDA-MB-231.
Transient transfection of MDA-MB-231 breast cancer cells has been described previously [ 19 ] . Briefly, 2 μg 3TP-Luc together with 0.3 μg β-galactosidase expression plasmid were transfected into cells grown to 70-80% confluency in 6-well plates using LipofectAMINE reagent (Invitrogen) following the manufacturers protocol.
The cell lines that express little or no BP1 (Hs578T, MDA-MB-435S, and MCF10A) are not tumorigenic, whereas MCF7ADR, MDA-MB-468, and MDA-MB-231 express BP1 and are tumorigenic.