Words similar to mda-mb-

Example sentences for: mda-mb-

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We have previously demonstrated that TGFβ upregulates PTHrP and PAI-1 RNA levels in MDA-MB-231 cells [ 19 ] . TGFβ affected PTHrP expression primarily by increasing the level of the promoter P3-specific transcript [ 19 ] . Quantitative PCR analysis using primers allowing the detection of PTHrP P3 and PAI-1 transcripts indicated that incubation of MDA-MB-231 cells with SB-202190 and SB-203580 greatly inhibited TGFβ-induced increase in PTHrP and, to a lesser extent, PAI-1 mRNA levels (Fig.
Standard curves (cycle threshold values versus template concentration) were prepared for each target and for the endogenous reference (GAPDH) using cDNA from MDA-MB-435 breast cells as the calibrator.
Nude mice bearing growing MDA-MB-231 human breast carcinoma xenografts were then divided into four dietary groups (20 mice per group) such that the mean tumor size was not different between groups.
We wanted to know to what extent SB-202190 and SB-203580 interfere with TGFβ-dependent Smad3 nuclear import in the invasive MDA-MB-231 breast cancer cell line.
Our findings in the MDA-MB-435 metastasis model are in agreement with TSP-1 playing a role in the reduction of metastatic potential [ 2 ] . Clinically, TSP-1 expression is inversely correlated with tumor grade and survival rate in a number of cancers [ 28 29 ] , most probably because of the anti-angiogenic effect of TSP-1.