Words similar to mda-mb-

Example sentences for: mda-mb-

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1, the levels of BP1 expression varied widely between the cell lines, from barely detectable (Hs578T, MDA-MB-435S, and MCF10A; lanes 2, 6, and 9, respectively) to highly expressing (MCF7ADR, MDA-MB-468, and T-47D; lanes 4, 7, and 8, respectively); MCF7 and MDA-MB-231 (lanes 3 and 5, respectively) showed intermediate expression.
In an effort to establish a methodological framework for analysis of the molecules and the mechanisms involved in this complex multistep process, we previously developed a well-defined experimental system in which the role of candidate genes can be screened and tested [ 2 ] . By serial dilution cloning of the MDA-MB-435 tumor cell line and screening by orthotopic implantation into the mammary fat pad of athymic mice, we derived a pair of breast tumor cell lines (M-4A4 and NM-2C5) that originate from the same breast tumor, but that have diametrically opposite metastatic capabilities.
Here we show that, in the highly invasive breast cancer cell line MDA-MB-231, the SB-202190 and SB-203580 inhibitors negatively altered Smad3 nuclear entry upon TGFβ stimulation.
Primary tumors recovered from nude mice inoculated with the M-4A4 and NM-2C5 MDA-MB-435 clones [ 2 ] were used as positive controls.
In order to test whether TGFβ 1 signaling via α V β 6 is specific for SMAD4 deleted BxPC-3 cells or if this is a general phenomenon, we investigated signaling in TGFβ 1 -sensitive carcinoma cell lines HeLa, MCF-7 and MDA-MB-231.