Example sentences for: mda-mb-

How can you use “mda-mb-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We wanted to know to what extent SB-202190 and SB-203580 interfere with TGFβ-dependent Smad3 nuclear import in the invasive MDA-MB-231 breast cancer cell line.

  • Such genes are important targets at early-stage carcinogenesis, where TGFβ has a tumor-suppressive rather than a tumor-promoting function [ 28 ] . In addition, e.g. p21 protein is not dectable in MDA-MB-231 cells [ 29 ] .

  • We have previously characterized an experimental system that enables comparative molecular screening and functional evaluation of candidate breast metastasis-related genes in an isogenic background [ 2 ] . Two independent clones of opposing metastatic phenotype were derived from the MDA-MB-435 breast tumor cell line (metasatic M-4A4 and nonmetastatic NM-2C5 cell lines).

  • Standard curves (cycle threshold values versus template concentration) were prepared for each target and for the endogenous reference (GAPDH) using cDNA from MDA-MB-435 breast cells as the calibrator.

  • Primary tumors recovered from nude mice inoculated with the M-4A4 and NM-2C5 MDA-MB-435 clones [ 2 ] were used as positive controls.


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