Example sentences for: mda

How can you use “mda” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A first one is the CCR4-NOT multi-subunit group of proteins, which comprises at least two complexes of 1.0 and 1.9 MDa.

  • We were curious to know whether the expression changes observed in LNCaP would also occur in other androgen-responsive human prostate cancer cell lines (MDA PCa 2a, MDA PCa 2b, and LAPC-4), or in LNCaP and LAPC-4 subclones carried in androgen-depleted conditions for extended periods.

  • For example, the transcript levels of 310 of these genes changed by 1.5-fold or more in MDA PCa 2a and 2b cells following 48 hours of exposure to R1881; transcripts for 262 genes changed by 1.5-fold or greater in single treatments of all four LNCaP androgen-deprived subclones; and transcripts for 81 genes changed by 1.5-fold or greater in the three LAPC-4 and LAPC-4 (androgen-deprived) array experiments.

  • In yeast, yCCR4 is one of the components of the 1.0 MDa CCR4-NOT complex, which also includes yPOP2 and at least five yNOT proteins.

  • The global architectures of the yeast and vertebrate NPCs are highly similar, although there may be differences in the core ring structures [ 4 ] . Genetic and biochemical studies in yeast have identified ~30 NPC proteins (termed nucleoporins, Nups) that comprise the estimated ~44 MDa structure [ 5 ] . Recent proteomic analysis has determined that mammalian NPCs are also comprised of ~30 different proteins [ 6 ] ; however, the overall size of the vertebrate NPC is predicted to be larger [ 3 6 7 8 ] . Despite their size differences, yeast and vertebrate NPCs are responsible for identical transport reactions, and therefore, both structures are predicted to be functionally equivalent [ 9 ] .


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