Words similar to mda
Example sentences for: mda
How can you use “mda” in a sentence? Here are some example sentences to help you improve your vocabulary:
In yeast, yCCR4 is one of the components of the 1.0 MDa CCR4-NOT complex, which also includes yPOP2 and at least five yNOT proteins.
The 1.0 MDa complex contains yCCR4, yPOP2 (also referred to as yCAF1) and at least five yNOT1-5 proteins [ 5 6 7 ] . In this complex, yPOP2 independently binds to yCCR4 and yNOT1, and is absolutely required for yCCR4 to associate with the 1.0 MDa complex [ 6 7 ] . In the 1.9 MDa complex, yCCR4 binds to proteins such as yDBF2, a cell-cycle regulated protein kinase [ 2 ] , yCAF4 and yCAF16, and is essential for the interaction of both yCAF4 and yCAF16 with ySRB9, a component of the RNA polII holoenzyme [ 8 ] . yCCR4 was also reported to be associated with Paf1, Cdc73, and Hpr1 in a RNA polII complex distinct from the SRBP-containing holoenzyme [ 9 ] . Accordingly, yCCR4 contains, in its central region, a leucine-rich repeat (LRR) domain [ 10 ] which was demonstrated to be necessary for yCCR4 binding to the yPOP2 [ 5 11 ] , yDBF2 [ 2 ] , yCAF4 and yCAF16 [ 8 ] components of the CCR4-NOT complex.
MDA reacts with TBA to form a 1:2 MDA-TBA adduct that absorbs at 532 nm.
The global architectures of the yeast and vertebrate NPCs are highly similar, although there may be differences in the core ring structures [ 4 ] . Genetic and biochemical studies in yeast have identified ~30 NPC proteins (termed nucleoporins, Nups) that comprise the estimated ~44 MDa structure [ 5 ] . Recent proteomic analysis has determined that mammalian NPCs are also comprised of ~30 different proteins [ 6 ] ; however, the overall size of the vertebrate NPC is predicted to be larger [ 3 6 7 8 ] . Despite their size differences, yeast and vertebrate NPCs are responsible for identical transport reactions, and therefore, both structures are predicted to be functionally equivalent [ 9 ] .
yDBF2, yCAF4 and yCAF16) of the 1.9 MDa CCR4-NOT complex.
Loading...