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Example sentences for: mdah

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Using this approach, we determined that PTEN mRNA was increased up to 5-fold in MDAH cells and 4-fold in 10T1/2 cells.
In conclusion, MDAH cells (p53-negative), 10T1/2 cells (p53-positive), and TR9-7 cells (high or low levels of p53) all exhibited similarly increased expression levels of PTEN in response to the disruption of cell-matrix interactions.
After having established that PTEN protein phosphatase activity could be determined specifically, we transferred MDAH cells to suspension culture conditions and measured PTEN activity at various times afterwards.
As MDAH cells themselves are p53-negative, we used MDAH cells stably transfected with a tetracycline-regulated p53 gene, called TR9-7 [ 42 ] . These TR9-7 cells were pre-treated with or without tetracycline in monolayer culture.
As shown in Figure 5, the detachment of MDAH cells from their matrix resulted in decreased tyrosine-specific phosphorylation of FAK.