Example sentences for: mdck

How can you use “mdck” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To better understand the regulation of cPLA 2 by the MEK1/ERK pathway and Ca 2+, we investigated the effect of MEK inhibitors on AA release, cPLA 2 phosphorylation of Ser 505, cPLA 2 translocation kinetics, and [Ca 2+] i increase in Madin-Darby canine kidney (MDCK) cells.

  • MDCK cells were induced to express AQP1 by infection with replication-deficient adenovirus (see Materials and Methods).

  • MDCK cells transfected with empty virus showed no augmentation of transepithelial water movement, confirming previous work that showed water does not flow across tight junctions in MDCK confluent layers [ 16 ] . Cells transfected with empty virus also showed no effect of TEA treatment.

  • TEA inhibition of water flux in AQP1-expressing MDCK cells

  • 1 cells, without constitutively active ERKs, AA release is delayed after [Ca 2+] i mobilization, and is temporally correlated with ERK activation [ 40 ] , whereas in MDCK cells with constitutively active ERKs, AA release is rapid, with significant AA release measured 30 s after [Ca 2+] i increase [ 15 ] . This temporal correlation between AA release and ERK activation has also been reported in CHO cells in response to PAF stimulation [ 35 41 ] . These results support the observations made here that ERK activity is required for phospholipid hydrolysis independently of cPLA 2 translocation.


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