Example sentences for: leucovorin

How can you use “leucovorin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Potentiation of the anti-tumor activity of 5-FU by methotrexate (MTX) and leucovorin (LV) requires careful scheduling to achieve the most favorable interactions between these 3 drugs.

  • At hour 36 a 2 hour intravenous infusion of leucovorin was administered at a dose of 500 mg/m 2. Midway through the leucovorin infusion, 5-FU at a dose of 600 mg/m 2was given as a 30 minute intravenous bolus infusion.

  • This trial was also a randomized metastatic colorectal cancer study, comparing a new chemotherapy standard of care, 5-FU/leucovorin/CPT [ 24 25 ] to standard of care plus SU5416.

  • In the first trial (designated Trial A), the standard of care chemotherapy consisted of weekly administration of 5-FU and leucovorin (Roswell Park regimen); in the second trial (designated Trial B), the standard of care chemotherapy consisted of weekly or bi-weekly administration of 5-FU, leucovorin, and Irinotecan (CPT-11).

  • [ 10 ] A vast series of pre-clinical and clinical studies have suggested 5-FU is a more active anti-tumor agent when modulated by a host of compounds including leucovorin, [ 11 12 13 ] methotrexate, [ 14 ] folinic acid, [ 15 16 ] N-phosphonacetyl-L-aspartic acid (PALA) [ 17 18 19 20 21 22 ] and recombinant interferon alfa-2a (IFNaα-2a).


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