Words similar to leucine
Example sentences for: leucine
How can you use “leucine” in a sentence? Here are some example sentences to help you improve your vocabulary:
The most abundant amino acids in transmembrane regions are leucine, isoleucine, valine, phenylalanine, alanine, glycine, serine, and threonine.
On the other hand, while Ala135 is 8.5A away from the docked agonists, a leucine could make some hydrophobic interaction with nicotine and acetylcholine.
Thus, some of the observed ERβ specificity is probably a consequence of an unexpected ability to tolerate the absence of a leucine residue at the N-terminus of the LXXLL motif.
C/EBP is previously reported to be an important accessory factor for transactivation by several other transcription factors [ 26 ] . C/EBPβ was shown to transactivate the α1-acid glycoprotein gene promoter even when mutated in the DNA-binding domain, and this activation appeared to depend on protein-protein interaction with glucocorticoid receptor through the leucine zipper region [ 27 ] . Recently, a conserved domain in C/EBPα and C/EBPβ was shown to mediate cAMP responsiveness, strengthening the fact that C/EBP may be characterized as a cAMP-responsive nuclear regulator [ 28 29 ] . On the COX-2 promoter in granulosa cells, cAMP-mediated regulation was shown to be mediated primarily by an E-box that bind USF1 and USF2 isoforms in a manner resembling the RIIβ E-box in Sertoli cells [ 30 ] . Transactivation of the COX-2 gene in skin carcinoma cells is highly dependent on this E-box together with a C/EBP binding site that bind C/EBPβ and C/EBPδ [ 31 ] . These data strengthens a model of formation of a cAMP-responsive unit (CRU) containing USF and C/EBP.
In addition to these domains there are two leucine zippers starting at base pairs 484 and 505 suggesting protein-protein interaction.
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