Words similar to lcrg-lcrv
Example sentences for: lcrg-lcrv
How can you use “lcrg-lcrv” in a sentence? Here are some example sentences to help you improve your vocabulary:
Evidence accumulated to date clearly demonstrates that the LcrG-LcrV interaction is critical for the regulation of this complex virulence system [ 18 20 ] . Therefore, dissection of the LcrG-LcrV interaction is warranted.
The alanine at position 16 was previously identified as a critical residue in the LcrG-LcrV interaction [ 20 ] . Two mutations were characterized at this position (A16R and A16D) and they failed to interact with LcrV, showing that single substitutions of this kind can disrupt the LcrG-LcrV interaction [ 20 ] . Additional data from this study showed that a substitution of the leucine at position 30 with an arginine also prevented the LcrG-LcrV interaction in yeast (Table 2).
Utilizing yeast two-hybrid analyses, we further investigated the LcrG-LcrV interaction.
As coiled-coil motifs show a characteristic seven amino acid repeat pattern, with each repeat representing two turns of the α-helix, it is interesting that three positions identified as important to the LcrG-LcrV interaction (16, 23, and 30) are each separated by seven amino acids.
These results suggest that the LcrG-LcrV interaction requires the N-terminus of LcrG and may involve a coiled-coil domain.