Example sentences for: lcrg

How can you use “lcrg” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • LcrG and LcrV physically interact in Y. pestis [ 4 ] , and that interaction plays a significant role in the regulation of Yops secretion [ 20 ] . LcrG and LcrV interact in a yeast two-hybrid assay [ 20 ] , therefore this technique was used to further investigate the region of LcrG required for its interaction with LcrV.

  • Mutagenesis of the serine at position 23 to arginine resulted in an LcrG variant that weakly interacted with LcrV as determined by a filter-lift assay for β-galactosidase activity.

  • Surprisingly, the alanine-scanning mutagenesis results failed to demonstrate amino acids of LcrG involved in the LcrG-LcrV interaction.

  • Analysis of the putative secretion-blocking region of LcrG

  • This result suggested that mutagenesis of pcrG could be used to isolate PcrG mutants capable of blocking Yops secretion in Y. pestis . This genetic screen allowed the isolation of PcrG mutants that functioned in Y. pestis in a manner indistinguishable from LcrG (Fig.


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