Words similar to isotypes
Example sentences for: isotypes
How can you use “isotypes” in a sentence? Here are some example sentences to help you improve your vocabulary:
All of the five monoclonal antibodies were of IgM isotypes (Table 1).
Th1 and Th2 cytokines regulate PG-specific autoantibody IgG isotypes and susceptibility to arthritis.
One of the major cellular serine/threonine protein phosphatases is protein phosphatase type 1 (PP1) [ 1 ] . An abundant enzyme expressed in all cells, complex regulation of PP1 is thought to be essential for proper temporal and spatial regulation of PP1 catalytic activity towards individual substrates [ 2 ] . Three different isotypes of the catalytic subunit, designated PP1α, PP1δ, and PP1γ1, are expressed in many different cell types [ 3 ] . Studies employing many eukaryotic systems all point to a crucial role for PP1 activity in controlling cell cycle progression, and an absolute requirement of this activity for mitotic exit [ 4 5 6 7 ] . There is also evidence to suggest that phosphorylation of PP1 and its associated proteins by the cyclin-dependent kinases may regulate PP1 activity in a cell cycle stage-dependent manner [ 8 9 10 ] . Hence, current efforts are directed towards identification of cell cycle-dependent substrates for PP1, and how regulation of PP1 activity towards these substrates controls the cell division cycle.
We did not measure potential differences in guinea pig IgG isotypes.
For example, paclitaxel-resistant lung cancer cells and ovarian tumors were shown to have increased levels of tubulin isotypes, particularly β-tubulin classes III and IVa [ 28 ] . Furthermore, when paclitaxel-resistant lung cancer cells were treated with antisense oligonucleotides for β-tubulin class III, the drug resistance was partly reversed, coincident with decreased protein levels of β-tubulin class III [ 65 ] . However, it should be noted that β-tubulin classes I, II, III, and IVa all increased significantly in paclitaxel-resistant lung cancer cells, indicating that the drug effect did not uniquely involve a single tubulin isotype.
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